Alkermes Incorporated

Alkermes, Inc. is applying the tools of biotechnology to the development of sophisticated proprietary drug delivery systems. Alkermes is developing product candidates based on its independent drug delivery technologies: ProLease(R), which is designed to enable single injections lasting a few days to several months to be made of proteins or peptides otherwise given by more frequent injection; Cereport(TM) (formerly known as RMP-7(TM)), which is designed to enable increased drug delivery to the brain by transiently opening the blood-brain barrier; and Medisorb(R), which extends Alkermes' technology for injectable sustained release and is designed for more traditional small molecule pharmaceutical compounds.

Contact Details: 64 Sidney Street Cambridge MA 02139-4234 United States of America Tel: 617 494 0171 Fax: 617 494 9263 Email: financial@alkermes.com WWW: www.alkermes.com/

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Recent Publications by Alkermes Incorporated:
Points to Consider when Establishing Drug Product Specifications for Parenteral Microspheres. Drug product specifications are a critical element of a good control...	19th November, 2009	Formulation Development, Alkermes Inc, Cambridge, Massachusetts, USA,	AAPS J. 2009 Nov 17. DOI Direct Link
Acanthosis Nigricans Identifies Youth at High Risk for Metabolic Abnormalities. OBJECTIVE: To determine the prevalence of abnormal glucose homeostasis and...	3rd October, 2009	Division of Endocrinology, Children's Memorial Hospital (W.B.) and the	J Pediatr. 2009 Sep 29. DOI Direct Link
A link between adolescent nicotine metabolism and smoking topography. Adult slow nicotine metabolizers have lower smoke exposure, carbon...	26th June, 2009	National Institute on Drug Abuse Intramural Research Program, National	Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1578-83. DOI Direct Link
Route of administration affects the ability of naltrexone to reduce amphetamine-potentiated brain stimulation reward in rats. Opioid receptor antagonism has been shown to attenuate behavioral and...	6th June, 2009	Department of Life Sciences and Toxicology, Alkermes, Inc., USA.	Addict Biol. 2009 Sep;14(4):408-18. Epub 2009 Jun 1. DOI Direct Link
Implementation of a low-cost Interim 21CFR11 compliance solution for laboratory environments. In the recent past, compliance with 21CFR11 has become a major buzzword...	18th October, 2008	Alkermes Inc. 88 Sidney Street Cambridge MA 02139 USA.	J Autom Methods Manag Chem. 2003;25(3):69-71. DOI Direct Link
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BioNews Results for Alkermes Incorporated:
Alkermes Begins Phase 2 Clinical Study of ALKS 33 for the Treatment of Alcohol Dependence	TradingMarkets:  Nov 21 2009 4:02AM Matching: alkermes
Alkermes Begins Phase 2 Clinical Study of ALKS 33 for the Treatment of Alcohol Dependence	Individual.com:  Nov 21 2009 6:40AM Matching: alkermes
Alkermes Begins Phase 2 Clinical Study of ALKS 33 for the Treatment of Alcohol Dependence	Individual.com:  Nov 21 2009 6:38AM Matching: alkermes
PHARMACEUTICAL: High-speed video quantifies drug delivery performance	Vision Systems Design:  Nov 21 2009 2:36AM Matching: alkermes
Alkermes initiates Phase II alcohol dependence study	Individual.com:  Nov 20 2009 9:40AM Matching: alkermes
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Alkermes Incorporated Clinical Trials:
The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis

Alkermes Incorporated Patents:
US Patent No.	Title
6495164	Preparation of injectable suspensions having improved injectability
6667061	Preparation of injectable suspensions having improved injectability
6703477	Acid end group poly(D,L-lactide-co-glycolide) copolymers with high glycolide content
6705757	Method and apparatus for preparing microparticles using in-line solvent extraction
6713087	Method of producing submicron particles of a labile agent and use thereof
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