Recent Publications by Entelos Incorporated: |
The liver pharmacological and xenobiotic gene response repertoire.
We have used a supervised classification approach to systematically mine a... | 22nd April, 2008
| Iconix Biosciences now
| Mol Syst Biol. 2008;4:175. Epub 2008 Mar 25.
DOI Direct Link |
A geometrical model of dermal capillary clearance.
A new microscopic model is developed to describe the dermal capillary... | 25th October, 2007
| University at Buffalo, State University of New York, Department of
| Math Biosci. 2007 Aug;208(2):430-53. Epub 2006 Nov 14.
DOI Direct Link |
Dosing and timing effects of anti-CD40L therapy: predictions from a mathematical model of type 1 diabetes.
Several publications describing the use of anti-CD40L monoclonal... | 26th July, 2007
| Entelos, Inc., 110 Marsh Drive, Foster City, CA 94404, USA.
| Ann N Y Acad Sci. 2007 Apr;1103:63-8. Epub 2007 Mar 21.
DOI Direct Link |
The virtual NOD mouse: applying predictive biosimulation to research in type 1 diabetes.
Type 1 diabetes is a complex, multifactorial disease characterized by T... | 26th July, 2007
| Entelos, Inc., 110 Marsh Drive, Foster City, CA 94404, USA.
| Ann N Y Acad Sci. 2007 Apr;1103:45-62. Epub 2007 Mar 21.
DOI Direct Link |
In silico prediction of clinical efficacy.
Drug development is a high risk and costly process, and the ability to... | 8th February, 2007
| Entelos, Inc., 110 Marsh Drive, Foster City, CA 94404, USA.
| Curr Opin Biotechnol. 2006 Dec;17(6):666-70. Epub 2006 Oct 12.
DOI Direct Link |
Mechanisms mediating anti-CD3 antibody efficacy: insights from a mathematical model of type 1 diabetes.
Anti-CD3 antibody therapy, a promising clinical approach for the treatment... | 11th January, 2007
| Entelos Inc., 110 Marsh Drive, Foster City, CA 94404, USA.
| Ann N Y Acad Sci. 2006 Oct;1079:369-73.
DOI Direct Link |
Application of predictive biosimulation within pharmaceutical clinical development: examples of significance for translational medicine and clinical trial design.
The challenge of accurately predicting human clinical outcome based on... | 26th October, 2006
| Entelos
| Syst Biol (Stevenage). 2005 Dec;152(4):214-20.
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The impact of systems biology and biosimulation on drug discovery and development.
Drug discovery and development involves a series of difficult, systematic... | 13th October, 2006
| Silico R&D, Entelos, Inc., 110 Marsh Drive, Foster City, CA 9440, USA.
| Mol Biosyst. 2006 Jun;2(6-7):288-91. Epub 2006 May 18.
DOI Direct Link |
A comprehensive review of interventions in the NOD mouse and implications for translation.
Type 1 diabetes (T1D) animal models such as the nonobese diabetic (NOD)... | 6th October, 2005
| Entelos Inc., Foster
| Immunity. 2005 Aug;23(2):115-26.
DOI Direct Link |
In silico modeling and simulation of bone biology: a proposal.
Contemporary, computer-based mathematical modeling techniques make it... | 21st September, 2005
| In Silico R&D Department, Entelos, Inc., Foster City, California, USA.
| J Bone Miner Res. 2005 Jul;20(7):1079-84. Epub 2005 Apr 4.
DOI Direct Link |
Predictive biosimulation and virtual patients in pharmaceutical R and D.
In the automotive, telecommunication, and aerospace industries, modeling... | 27th August, 2005
| Entelos, Inc., 110 Marsh Dr., Foster City, CA 94404, USA.
| Stud Health Technol Inform. 2005;111:37-42.
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Modeling approaches to type 2 diabetes.
The incidence of type 2 diabetes is increasing rapidly, but clinical... | 24th September, 2004
| Entelos, Inc., Foster
| Diabetes Technol Ther. 2004 Feb;6(1):39-47.
DOI Direct Link |
Assessing the impact of predictive biosimulation on drug discovery and development.
Systems biology is creating a context for interpreting the vast amounts of... | 21st September, 2004
| Entelos, Inc., 110 Marsh Dr., Foster City, CA 94404, USA.
| J Bioinform Comput Biol. 2003 Apr;1(1):169-77.
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Small- and large-scale biosimulation applied to drug discovery and development.
Biosimulation uses mathematics to quantitatively represent the dynamics of... | 21st February, 2003
| Entelos, Inc.,4040 Campbell Ave., Ste. 200, Menlo Park, CA 94025, USA.
| Drug Discov Today. 2002 Oct 15;7(20 Suppl):S192-6.
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Factors affecting the deposition of inhaled porous drug particles.
Recent findings indicate that the inhalation of large manufactured porous... | 12th December, 2002
| Entelos, Inc, Menlo Park, California 94025, USA.
| J Pharm Sci. 2002 Jul;91(7):1590-600.
DOI Direct Link |
