Enzon Incorporated

Enzon Incorporated is a biopharmaceutical company that develops, manufactures and markets enhanced therapeutics for life-threatening diseases through the application of its two proprietary technologies: (i) polyethylene glycol ("PEG") Modification or the PEG Process and (ii) single-chain antigen-binding ("SCA(R)") proteins. Enzon is focusing its internalresearch activities on applying its proprietary technologies to compounds of known therapeutic efficacy in order to enhance the performance of these compounds. Enzon is commercializing its proprietary technologies by developing products internally and in cooperation with strategic partners. To date, Enzon and its partners have successfully commercialized two products, ONCASPAR(R) and ADAGEN(R).

Contact Details: 20 Kingsbridge Road Piscataway NJ 08854 United States of America Tel: 732 980 4500 Fax: 732 980 5911 Email: WWW: www.enzon.com/

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Recent Publications by Enzon Incorporated:
Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model. PURPOSE: Clinical development of SN38, the active metabolite of...	21st May, 2008	Enzon Pharmaceuticals, Inc., Piscataway, New Jersey 08854, USA.	Clin Cancer Res. 2008 Mar 15;14(6):1888-96. DOI Direct Link
Releasable PEGylation of proteins with customized linkers. Releasable PEGylation employs customized linkers that reversibly tether a...	6th May, 2008	Enzon Pharmaceuticals, Inc., 20 Kingsbridge Road, Piscataway, New Jersey	Adv Drug Deliv Rev. 2008 Jan 3;60(1):29-49. Epub 2007 Aug 16. DOI Direct Link
Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers. CPT-11, also known as irinotecan, is a prodrug that is approved for the...	29th March, 2008	Enzon Pharmaceuticals, Inc., 20 Kingsbridge Road, Piscataway, New Jersey	Bioconjug Chem. 2008 Apr;19(4):849-59. Epub 2008 Mar 28. DOI Direct Link
Releasable PEGylation of mesothelin targeted immunotoxin SS1P achieves single dosage complete regression of a human carcinoma in mice. Recombinant immunotoxins exhibit targeting and cytotoxic functions needed...	30th August, 2007	Enzon Pharmaceuticals, Incorporated, 20 Kingsbridge Road, Piscataway, New	Bioconjug Chem. 2007 May-Jun;18(3):773-84. Epub 2007 Mar 9. DOI Direct Link
Antibody engineering and modification technologies. Antibody engineering has become a well-developed discipline, encompassing...	27th July, 2007	Enzon Pharmaceuticals, Piscataway, NJ 08854-3969, USA.	Biomol Eng. 2007 Jun;24(2):201-15. Epub 2007 Mar 31. DOI Direct Link
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BioNews Results for Enzon Incorporated:
High Growth Reported for the World Blood Banking & Blood Products Market	SkyNewswire.com:  Jun 29 2008 9:46PM Matching: enzon
Biotech Back From The Dead	Yahoo!:  Jun 27 2008 4:24PM Matching: enzon
High Growth Reported for the World Blood Banking & Blood Products Market	Market Wire:  Jun 27 2008 9:50PM Matching: enzon
ValuEngine Upgrades Brasil Telecom, Enzon Pharma To A 5 Rating	TMC Net:  Jun 25 2008 7:02AM Matching: enzon
ValuEngine Upgrades Brasil Telecom, Enzon Pharma To A 5 Rating	Calibre Macro World:  Jun 25 2008 3:38AM Matching: enzon
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Enzon Incorporated Patents:
US Patent No.	Title
5990275	Linker and linked fusion polypeptides
6180095	Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
6194580	High yield method for stereoselective acylation of tertiary alcohols
6214330	Coumarin and related aromatic-based polymeric prodrugs
6251382	Biodegradable high molecular weight polymeric linkers and their conjugates
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