Esperion

We discover and develop pharmaceutical products for the treatment of cardiovascular disease, which is disease of the heart and the body's blood vessels and related organs. We intend to commercialize a novel class of drugs that focus on a new treatment approach we call "HDL Therapy," which is based on our understanding of high density lipoprotein, or HDL, function. HDL is the primary facilitator of the reverse lipid transport, or RLT, pathway. The RLT pathway is responsible for removing excess cholesterol from arteries and other tissues and for its transport to the liver for elimination from the body. Our goal is to develop drugs that exploit the beneficial functions of HDL within the RLT pathway. We currently have five product candidates under development for the treatment of cardiovascular disease.

Contact Details: 3621 S. State Street, 695 KMS Place Ann Arbor MI 48108 United States of America Tel: (734) 332 0506 Fax: (734) 332 0516 Email: invester_relations@esperion.com WWW: www.Esperion.com/

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Recent Publications by Esperion:
Acute coronary artery injury in dogs following administration of CI-1034, an endothelin A receptor antagonist. The objective of this study was to characterize acute coronary artery...	19th August, 2006	Esperion Therapeutics, a Division of Pfizer Global Research and	Cardiovasc Toxicol. 2006;6(1):25-38.
Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids. A series of long (11-15) hydrocarbon chain diols and diacids with various...	17th February, 2006	Esperion Therapeutics, A Division of Pfizer Global Research and	J Med Chem. 2006 Jan 12;49(1):334-48. DOI Direct Link
Metabolomics applications of FT-ICR mass spectrometry. Metabolomics, also known as Metabolic Profiling, is an emerging discipline...	24th March, 2005	Esperion Therapeutics, Inc., Ann Arbor, Michigan 48108, USA.	Mass Spectrom Rev. 2005 Mar-Apr;24(2):223-31. DOI Direct Link
Effects of a novel dual lipid synthesis inhibitor and its potential utility in treating dyslipidemia and metabolic syndrome. We have identified a novel omega-hydroxy-alkanedicarboxylic acid, ESP...	1st March, 2005	Esperion Therapeutics, Inc., Ann Arbor, MI 48108, USA.	J Lipid Res. 2004 Jul;45(7):1289-301. Epub 2004 Apr 21. DOI Direct Link
HDL therapy for the acute treatment of atherosclerosis. Although pharmacologic intervention to treat atherosclerosis originally...	8th May, 2003	Esperion Therapeutics, Inc, 3621 South State Street, 695 KMS Place, Ann	Atheroscler Suppl. 2002 Dec;3(4):31-8.
→View more Esperion research publications.

BioNews Results for Esperion:
Update:Groups pool $3.5 million to buy former Esperion Therapeutics from Pfizer	Ann Arbor News:  Jul 24 2008 3:01AM Matching: esperion
Update:Groups pool $3.5 million to buy former Esperion Therapeutics from Pfizer	Business Review:  Jul 24 2008 12:18AM Matching: esperion
Former Pfizer Building In Plymouth To Become Pharma Incubator	WWJ Newsradio 950:  Jul 24 2008 2:41AM Matching: esperion
Michigan Economic Development Groups and Non-Profit Create Life Science and Innovation Center	KATC 3:  Jul 24 2008 12:32AM Matching: esperion
Michigan Economic Development Groups and Non-Profit Create Life Science and Innovation Center	TickerTech.com:  Jul 23 2008 11:54PM Matching: esperion
Promote your company here: BioNewsCast - Press Release Distribution	→View more Esperion news.

Esperion Patents:
US Patent No.	Title
7335799	Hydroxyl compounds and compositions for cholesterol management and related uses
6646170	Intermediates for the synthesis of ether compounds
6617134	Dimer of molecular variant of apolipoprotein and processes for the production thereof
6559284	Process for purifying a protein
6506879	Purified Apo A and Apo E compounds and methods for using them
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