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Esperion

We discover and develop pharmaceutical products for the treatment of cardiovascular disease, which is disease of the heart and the body's blood vessels and related organs. We intend to commercialize a novel class of drugs that focus on a new treatment approach we call "HDL Therapy," which is based on our understanding of high density lipoprotein, or HDL, function. HDL is the primary facilitator of the reverse lipid transport, or RLT, pathway. The RLT pathway is responsible for removing excess cholesterol from arteries and other tissues and for its transport to the liver for elimination from the body. Our goal is to develop drugs that exploit the beneficial functions of HDL within the RLT pathway. We currently have five product candidates under development for the treatment of cardiovascular disease.


Contact Details:
3621 S. State Street, 695 KMS Place
Ann Arbor
MI
48108
United States of America
Tel:(734) 332 0506
Fax:(734) 332 0516
Email:invester_relations@esperion.com
WWW:

www.Esperion.com/




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Recent Publications by Esperion:

Acute coronary artery injury in dogs following administration of CI-1034, an endothelin A receptor antagonist.
The objective of this study was to characterize acute coronary artery...
19th August, 2006
Esperion Therapeutics, a Division of Pfizer Global Research and Cardiovasc Toxicol. 2006;6(1):25-38.
Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids.
A series of long (11-15) hydrocarbon chain diols and diacids with various...
17th February, 2006
Esperion Therapeutics, A Division of Pfizer Global Research and J Med Chem. 2006 Jan 12;49(1):334-48.
DOI Direct Link
Metabolomics applications of FT-ICR mass spectrometry.
Metabolomics, also known as Metabolic Profiling, is an emerging discipline...
24th March, 2005
Esperion Therapeutics, Inc., Ann Arbor, Michigan 48108, USA. Mass Spectrom Rev. 2005 Mar-Apr;24(2):223-31.
DOI Direct Link
Effects of a novel dual lipid synthesis inhibitor and its potential utility in treating dyslipidemia and metabolic syndrome.
We have identified a novel omega-hydroxy-alkanedicarboxylic acid, ESP...
1st March, 2005
Esperion Therapeutics, Inc., Ann Arbor, MI 48108, USA. J Lipid Res. 2004 Jul;45(7):1289-301. Epub 2004 Apr 21.
DOI Direct Link
HDL therapy for the acute treatment of atherosclerosis.
Although pharmacologic intervention to treat atherosclerosis originally...
8th May, 2003
Esperion Therapeutics, Inc, 3621 South State Street, 695 KMS Place, Ann Atheroscler Suppl. 2002 Dec;3(4):31-8.

View more Esperion research publications.

Press Releases on Esperion:

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Esperion Therapeutics Initiates Phase I Clinical Study for ETC-1002 13th November, 2009 Esperion Therapeutics
PLYMOUTH, Mich., Nov. 13 /PRNewswire/ -- Esperion Therapeutics, a privately held biotechnology company working to discover, develop and commercialize treatments for cardiovascular and metabolic
Pharmalink AB Strengthens its Board of Directors and Signals a Strategic Step Towards Late Phase Product Development 23rd April, 2009
STOCKHOLM, April 23 /PRNewswire/ -- Pharmalink AB today announced that it has strengthened its Board of Directors as the company's portfolio continues to move towards late stage product
Sofinnova Partners Voted 2008 "European Venture Capital Firm of the Year" 25th March, 2009
PARIS, March 24 /PRNewswire/ -- Sofinnova Partners (http://www.sofinnova.fr), a Paris-based venture capital firm, announced today that it has been awarded the 2008 "European Venture Capital Firm
Velcura Therapeutics, Inc. Adds William Brinkerhoff to its Board of Directors 18th July, 2008 Velcura Therapeutics, Inc.
ANN ARBOR, Mich., July 18 /PRNewswire/ -- Velcura Therapeutics, Inc. CEO Michael Long, Ph.D., announced that William F. Brinkerhoff has joined the Board of Directors of the biotechnology company,
Cerenis Therapeutics Completes 25 Million Euros ($30.5 Million) Series A 1st August, 2005 Cerenis Therapeutics
Cerenis Therapeutics Completes 25 Million Euros ($30.5 Million) Series A Financing To Progress Hdl-Related Drugs For Cardiovascular Diseases Toulouse, France & Ann Arbor, Michigan,

BioNews Results for Esperion:

Esperion Therapeutics Initiates Phase I Clinical Study for ETC-1002
KOTA Territory News:  Nov 14 2009 11:05PM Matching: esperion
Esperion Therapeutics Initiates Phase I Clinical Study for ETC-1002
KSLA:  Nov 14 2009 7:29AM Matching: esperion
Esperion Therapeutics Initiates Phase I Clinical Study For ETC-1002
Medical News Today:  Nov 14 2009 10:16AM Matching: esperion
Esperion Therapeutics Initiates Phase I Clinical Study for ETC-1002
Pharmacy Choice:  Nov 14 2009 12:59AM Matching: esperion
Medical News: Esperion Therapeutics Initiates Phase I Clinical Study For ETC-1002
BioFind:  Nov 14 2009 12:57PM Matching: esperion
Promote your company here: BioNewsCast - Press Release Distribution

View more Esperion news.

Esperion Patents:

US Patent No.Title
7576130 Dihydroxyl compounds and compositions for cholesterol management and related uses
6646170 Intermediates for the synthesis of ether compounds
6617134 Dimer of molecular variant of apolipoprotein and processes for the production thereof
6559284 Process for purifying a protein
6506879 Purified Apo A and Apo E compounds and methods for using them

View more Esperion patents.

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