Recent Publications by Fibrogen: |
CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy.
In diabetic nephropathy, connective tissue growth factor (CTGF) is... | 18th July, 2008
| Departments of *Pathology and Nephrology, University Medical Center
| J Am Soc Nephrol. 2008 Jul 16.
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The ADAM17-amphiregulin-EGFR axis in mammary development and cancer.
In order to fulfill its function of producing and delivering sufficient... | 13th May, 2008
| FibroGen, Inc., 225 Gateway Boulevard, South San Francisco, CA 94080, USA,
| J Mammary Gland Biol Neoplasia. 2008 Jun;13(2):181-94. Epub 2008 May 10.
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Site-specific polymer modification of therapeutic proteins.
Recent advances in chemoselective ligation technology have made possible... | 14th February, 2006
| Gryphon Therapeutics, South San Francisco, CA 94080, USA.
| Curr Opin Chem Biol. 2005 Dec;9(6):555-60. Epub 2005 Oct 17.
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Recombinant microbial systems for the production of human collagen and gelatin.
The use of genetically engineered microorganisms is a cost-effective,... | 10th February, 2006
| FibroGen, Inc., 225 Gateway Boulevard, South San Francisco, CA 94080, USA.
| Appl Microbiol Biotechnol. 2005 Dec;69(3):245-52. Epub 2005 Nov 15.
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Expression and characterization of a low molecular weight recombinant human gelatin: development of a substitute for animal-derived gelatin with superior features.
Gelatin is used as a stabilizer in several vaccines. Allergic reactions to... | 1st July, 2005
| FibroGen, Inc. 225 Gateway Boulevard, South San Francisco, CA 94080, USA.
| Protein Expr Purif. 2005 Apr;40(2):346-57.
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Development of a recombinant human collagen-type III based hemostat.
Animal-tissue-derived collagen, containing mostly type I collagen with a... | 16th December, 2004
| Fibrogen, Inc., South San Francisco, California 94080, USA.
| J Biomed Mater Res B Appl Biomater. 2004 Apr 15;69(1):18-24.
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The application of recombinant human collagen in tissue engineering.
Collagen is the main structural protein in vertebrates. It plays an... | 30th June, 2004
| FibroGen Inc., 225 Gateway Boulevard, South San Francisco, CA 94080, USA.
| BioDrugs. 2004;18(2):103-19.
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Recombinant collagen and gelatin for drug delivery.
The tools of recombinant protein expression are now being used to provide... | 20th May, 2004
| FibroGen, Inc., 225 Gateway Boulevard, South San Francisco, CA 94080, USA.
| Adv Drug Deliv Rev. 2003 Nov 28;55(12):1547-67.
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Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts.
In skin, the profibrotic protein connective tissue growth factor (CTGF) is... | 4th July, 2003
| Fibrogen, Inc., South San Francisco, California 94080, USA.
| J Biol Chem. 2003 Apr 11;278(15):13008-15. Epub 2003 Feb 5.
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CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC.
BACKGROUND: The induction of excess matrix in renal fibrosis seems to be... | 26th February, 2003
| FibroGen, Inc., 225 Gateway Boulevard, South San Francisco, CA 94080, USA.
| Kidney Int. 2002 Oct;62(4):1149-59.
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