Recent Publications by Fidelity Systems Incorporated: |
Methoxyoxalamido chemistry in the synthesis of tethered phosphoramidites and functionalized oligonucleotides.
A general approach to phosphoramidites tethered with single and multiple... | 9th August, 2008
| Fidelity Systems, Inc., Gaithersburg, Maryland, USA.
| Curr Protoc Nucleic Acid Chem. 2006 Jul;Chapter 4:Unit 4.29.
DOI Direct Link |
Recent developments in the optimization of thermostable DNA polymerases for efficient applications.
We have developed a general route to the synthesis of novel amino linker... | 29th April, 2005
| Fidelity Systems Inc., 7961 Cessna Avenue, Gaithersburg, Maryland 20879,
| Trends Biotechnol. 2004 May;22(5):253-60.
DOI Direct Link |
Methoxyoxalamido chemistry in the synthesis of novel amino linker and spacer phosphoramidites: a robust means for stability, structural versatility, and optimal tether length.
We have developed a general route to the synthesis of novel amino linker... | 17th December, 2004
| Fidelity Systems Inc., 7961 Cessna Avenue, Gaithersburg, MD 20879, USA.
| Bioconjug Chem. 2004 May-Jun;15(3):569-75.
DOI Direct Link |
High-throughput production of optimized primers (fimers) for whole-genome direct sequencing.
Fimers are specifically modified primers selected to inhibit nonspecific... | 17th November, 2004
| Fidelity Systems Inc., Gaithresburg, MD, USA
| Methods Mol Biol. 2005;288:291-304.
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Biotin-labeled oligonucleotides with extraordinarily long tethering arms.
We describe synthesis of four novel biotin phosphoramidites with tethering... | 17th November, 2004
| Fidelity Systems Inc., Gaithersburg, MD, USA.
| Methods Mol Biol. 2005;288:225-40.
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Finishing "working draft" BAC projects by directed sequencing with ThermoFidelase and Fimers.
We have developed a general route to the synthesis of novel amino linker... | 20th May, 2004
| Fidelity Systems Inc., Gaithersburg, MD, USA.
| Methods Mol Biol. 2004;255:295-308.
DOI Direct Link |
Use of Fimers to eliminate polymerase chain reaction and primer-dimer artifacts and to increase yield in BAC-sequencing reactions.
We have developed a general route to the synthesis of novel amino linker... | 20th May, 2004
| Fidelity Systems Inc., Gaithersburg, MD, USA.
| Methods Mol Biol. 2004;255:221-9.
DOI Direct Link |
Novel biotin phosphoramidites with super-long tethering arms.
A number of novel biotin phosphoramidites, possessing exceptionally long... | 12th December, 2003
| Fidelity Systems, Inc., Gaithersburg, Maryland 20879, USA.
| Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1439-41.
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Stability, vigor, and inherent versatility of novel amino linker and spacer phosphoramidites.
Novel amino linker and spacer phosphoramidites were synthesized from... | 12th December, 2003
| Fidelity Systems, Inc., Gaithersburg, Maryland 20879, USA.
| Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1407-9.
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Helix-hairpin-helix motifs confer salt resistance and processivity on chimeric DNA polymerases.
Helix-hairpin-helix (HhH) is a widespread motif involved in... | 5th December, 2002
| Fidelity Systems, Inc., 7961 Cessna Avenue, Gaithersburg, MD 20879, USA.
| Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13510-5. Epub 2002 Oct 4.
DOI Direct Link |
