Biosearch Italia

Biosearch Italia is a leading European biotech company focused on the discovery, development and production of new antibiotics. Our goal is to prevent and treat infections caused by multi-resistant micro-organisms (bacteria and fungi) which do not respond to current therapy. Our work is based on high-throughput screening of a large and diverse library of microbial extracts, which is being constantly expanded. Our approach covers target identification, assay set up, chemical, microbiological and analytical profiling, bioinformatics, process development and supply of active ingredients.

Contact Details: Tel: Fax: Email: info@biosearch.it WWW: www.biosearch.it/

Recent Publications by Biosearch Italia:
Myxobacteria isolated in Israel as potential source of new anti-infectives. AIMS: To evaluate the patterns of the production of antimicrobial...	25th May, 2005	Vicuron Pharmaceuticals (formerly Biosearch Italia S.p.A), Gerenzano,	J Appl Microbiol. 2005;98(2):429-39. DOI Direct Link
Evaluation of phenylboronate agarose for industrial-scale purification of erythropoietin from mammalian cell cultures. The search for novel, cost-effective ways to produce erythropoietin (Epo),...	1st October, 2003	Lepetit Research Center, now BioSearch Italia, 21040 Gerenzano, Italy.	J Biotechnol. 2003 Mar 20;101(3):275-87.
Conexibacter woesei gen. nov., sp. nov., a novel representative of a deep evolutionary line of descent within the class Actinobacteria. A novel Gram-positive bacterial strain was isolated from forest soil....	12th August, 2003	Biosearch Italia, via Lepetit 34, 21040 Gerenzano (VA), Italy.	Int J Syst Evol Microbiol. 2003 Mar;53(Pt 2):569-76.
Changes in GE2270 antibiotic production in Planobispora rosea through modulation of methylation metabolism. Thiazolylpeptide GE2270 is a potent antibiotic inhibiting protein...	2nd August, 2003	Biosearch Italia S.p.A., Via R. Lepetit, 34, 21040 Gerenzano, Italy.	Microbiology. 2003 Jun;149(Pt 6):1523-32.
Production of demannosyl-A40926 by a Nonomuraea sp. ATCC 39727 mutant strain. Thiazolylpeptide GE2270 is a potent antibiotic inhibiting protein...	20th June, 2003	Biosearch Italia S.p.A. Via R. Lepetit, 34, 21040, Gerenzano (Varese)	J Antibiot (Tokyo). 2003 Mar;56(3):310-3.
→View more Biosearch Italia research publications.

Press Releases on Biosearch Italia:
The next Generation Antifungals: Triazoles vs Peptides	1st January, 1970	Bioseeker	BioSeeker report "The next Generation Antifungals: Triazoles vs Peptides" According to the Antifungal Work Group at NIH there

Biosearch Italia Patents:
US Patent No.	Title
6586393	Antibiotics GE 23077, pharmaceutically acceptable salts and compositions, and use thereof
6218505	Chemical process for preparing amide derivatives of antibiotic A 40926
6143739	Basic proline-amide derivatives of GE 2270 and GE 2270-like antibiotics
6080731	Dinucleoside-5', 5'-pyrophosphates administered to treat HIV
6040297	Dinucleoside-5',5'-pyrophosphates
→View more Biosearch Italia patents.

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