GlycoDesign Incorporated

GLYCODesign is a publicly traded biopharmaceutical company engaged in the discovery and clinical development of novel glycotherapeutics for the treatment of cardiovascular diseases, inflammatory diseases, cancer and infectious diseases. Focusing exclusively in the glycobiology field (study of the biology of carbohydrate containing molecules), GLYCODesign's goal is to become the world leader in the discovery, development and delivery of glycotherapeutics and related therapies.

Contact Details: 480 University Avenue, Suite 90 Toronto Ontario M5G 1V2 Canada Tel: (416) 593-6027 Fax: (416) 593-8988 Email: WWW: www.glycodesign.com/

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Recent Publications by GlycoDesign Incorporated:
Catalytic mechanism of the inverting N-acetylglucosaminyltransferase I: DFT quantum mechanical model of the reaction pathway and determination of the transition state structure. The complex N-glycan structures on glycoproteins play important roles in...	27th March, 2004	GlycoDesign, Inc., 480 University Avenue, Suite 900, Toronto, Ontario,	Glycobiology. 2003 Aug;13(8):559-66. Epub 2003 Apr 2. DOI Direct Link
On the reaction pathways and determination of transition-state structures for retaining alpha-galactosyltransferases. The catalytic mechanism of retaining glycosyltransferases is not yet...	7th January, 2004	GlycoDesign Inc., 480 University Avenue, Suite 900, Toronto, ON, Canada	Carbohydr Res. 2003 Apr 22;338(9):865-77.
Minimal catalytic domain of N-acetylglucosaminyltransferase V. UDP-GlcNAc: Manalpha1-6Manbeta-R beta1-6 N-acetylglucosaminyltransferase V...	19th August, 2000	GlycoDesign Inc., Toronto, Ontario, Canada.	Glycobiology. 2000 Jun;10(6):595-9.
A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors. Malignant transformation is accompanied by altered cell surface...	8th July, 2000	GlycoDesign	Anal Biochem. 2000 Apr 10;280(1):137-42. DOI Direct Link

GlycoDesign Incorporated Patents:
US Patent No.	Title
6897052	N-acetylglycosaminyl transferase genes
6593119	Core 2 .beta.-1,6-N-acetylglycosaminyltransferase gene
6395745	Alkaloid halide salts of swainsonine and methods of use
6051711	Synthesis of swainsonine salts
6048870	3, 5, and/or 6 substituted analogues of swainsonine processes for their preparation and their use as therapeutic agents
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