Recent Publications by Celera Genomics: |
Finding homologs to nucleotide sequences using network BLAST searches.
Basic Local Alignment Search Tool (BLAST) can identify possible homologs... | 17th September, 2008
| Celera Genomics, Foster City, California, USA.
| Curr Protoc Bioinformatics. 2002 Aug;Chapter 3:Unit 3.3.
DOI Direct Link |
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase.
BLAST, Basic Local Alignment Search Tool is used more frequently than any... | 17th July, 2008
| Department of Medicinal Chemistry, Celera Genomics, 180 Kimball Way, South
| ChemMedChem. 2007 Jan;2(1):58-61.
DOI Direct Link |
Finding homologs in amino acid sequences using network BLAST searches.
BLAST, Basic Local Alignment Search Tool is used more frequently than any... | 15th May, 2008
| Celera Genomics, Foster City, California and Research Group for
| Curr Protoc Bioinformatics. 2003 Feb;Chapter 3:Unit 3.4.
DOI Direct Link |
Systematic identification of pseudogenes through whole genome expression evidence profiling.
The identification of pseudogenes is an integral and significant part of... | 31st October, 2006
| Celera Genomics, 45 West Gude Dr, Rockville, MD 20850, USA.
| Nucleic Acids Res. 2006;34(16):4477-85. Epub 2006 Aug 31.
DOI Direct Link |
Expression and characterization of recombinant gamma-tryptase.
Tryptases are trypsin-like serine proteases whose expression is restricted... | 19th October, 2006
| Department of Molecular Biology, Celera Genomics, 180 Kimball Way, South
| Protein Expr Purif. 2006 Sep;49(1):47-54. Epub 2006 May 23.
DOI Direct Link |
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivo.
Novel analogs of (-)-saframycin A are described. The analogs are shown to... | 17th October, 2006
| Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA.
| Bioorg Med Chem Lett. 2006 Sep 15;16(18):4884-8. Epub 2006 Jul 25.
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Potent 4-amino-5-azaindole factor VIIa inhibitors.
The 4-amino-5-azaindole as an amidino-benzimidazole replacement is... | 17th October, 2006
| Celera Genomics, South
| Bioorg Med Chem Lett. 2006 Sep 1;16(17):4567-70. Epub 2006 Jun 21.
DOI Direct Link |
Discovery and structure-activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers.
As a continuation of our efforts to discover novel apoptosis inducers as... | 17th October, 2006
| Celera Genomics, South
| Bioorg Med Chem Lett. 2006 Sep 1;16(17):4554-8. Epub 2006 Jun 19.
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CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo.
CRA-026440 is a novel, broad-spectrum, hydroxamic acid-based inhibitor of... | 13th October, 2006
| Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA.
| Mol Cancer Ther. 2006 Jul;5(7):1693-701.
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Design and synthesis of tetracyclic nonpeptidic biaryl nitrile inhibitors of cathepsin K.
The synthesis and biological profile of a novel series of potent and... | 7th October, 2006
| Celera Genomics, South San Francisco, CA 94080, USA.
| Bioorg Med Chem Lett. 2006 Aug 15;16(16):4296-9. Epub 2006 Jun 5.
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Novel, potent, selective, and orally bioavailable human betaII-tryptase inhibitors.
The synthesis of novel [1,2,4]oxadiazoles and their structure-activity... | 12th September, 2006
| Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA.
| Bioorg Med Chem Lett. 2006 Aug 1;16(15):4085-9. Epub 2006 May 24.
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Identification of metabolites of the tryptase inhibitor CRA-9249: observation of a metabolite derived from an unexpected hydroxylation pathway.
The metabolites of the tryptase inhibitor CRA-9249 were identified after... | 12th September, 2006
| Department of Drug Metabolism and Pharmacokinetics, Celera Genomics, 180
| Bioorg Med Chem Lett. 2006 Aug 1;16(15):4053-8. Epub 2006 May 18.
DOI Direct Link |
CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo.
CRA-024781 is a novel, broad spectrum hydroxamic acid-based inhibitor of... | 15th August, 2006
| Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA.
| Mol Cancer Ther. 2006 May;5(5):1309-17.
DOI Direct Link |
Structure-guided design of peptide-based tryptase inhibitors.
Improved peptide-based inhibitors of human beta tryptase were discovered... | 9th August, 2006
| Celera Genomics, Inc., 180 Kimball Way, South San Francisco, California
| Biochemistry. 2006 May 16;45(19):5964-73.
DOI Direct Link |
Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors.
Using a scaleable, directed library approach based on orthogonally... | 3rd August, 2006
| Celera Genomics, 180 Kimball Way, South San Francisco, CA 94080, USA.
| Bioorg Med Chem Lett. 2006 Jul 1;16(13):3434-9. Epub 2006 Apr 27.
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