Recent Publications by Hexos Incorporated: |
Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: a nutritional perspective of diabetes, obesity, and cancer.
Traditionally, nutrients such as glucose and amino acids have been viewed... | 11th November, 2006
| Hexos Inc., 18304 NE 153rd Street, Woodinville, WA 98072, USA.
| Sci STKE. 2006 Aug 1;2006(346):re7.
DOI Direct Link |
Turnover and characterization of UDP-N-acetylglucosaminyl transferase in a stably transfected HeLa cell line.
To estimate the turnover of UDP-N-acetylglucosaminyl transferase (OGT), we... | 13th July, 2005
| Hexos,
| Biochem Biophys Res Commun. 2005 Jun 24;332(1):263-70.
DOI Direct Link |
Glucosamine induces rapid desensitization of glucose transport in isolated adipocytes by increasing GlcN-6-P levels.
We have examined the hypothesis that glucosamine (GlcN) can rapidly induce... | 17th May, 2005
| Hexos
| Biochem Biophys Res Commun. 2005 Apr 15;329(3):1155-61.
DOI Direct Link |
Glucosamine-induced activation of glycogen biosynthesis in isolated adipocytes. Evidence for a rapid allosteric control mechanism within the hexosamine biosynthesis pathway.
Enhanced flux through the hexosamine biosynthesis pathway (HBP) induces... | 22nd April, 2005
| Hexos, Incorporated, Woodinville,
| J Biol Chem. 2005 Mar 25;280(12):11018-24. Epub 2005 Jan 12.
DOI Direct Link |
Potential regulation of nuclear UDP-N-acetylglucosaminyl transferase (OGT) by substrate availability: ability of chromatin protein to bind UDP-N-acetylglucosamine and reduce OGT-mediated O-Linked glycosylation.
UDP-N-acetylglucosaminyl transferase (OGT) resides in both cytosolic and... | 19th March, 2005
| Hexos, Inc, Woodinville,
| Biol Pharm Bull. 2004 Aug;27(8):1293-6.
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Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes: differential effects on glucosamine 6-phosphate, UDP-N-acetylglucosamine, and ATP levels.
Glucose and glucosamine (GlcN) cause insulin resistance over several hours... | 16th February, 2005
| Hexos, Inc., Woodinville, Washington 98072, USA.
| J Biol Chem. 2004 Aug 20;279(34):35313-9. Epub 2004 Jun 15.
DOI Direct Link |
Differential effects of vanadate on UDP-N-acetylglucosaminyl transferase activity derived from cytosol and nucleosol.
UDP-N-acetylglucosaminyl transferase (OGT) is a key enzyme of a novel... | 20th July, 2004
| Hexos,
| Biochem Biophys Res Commun. 2004 Jun 11;318(4):911-5.
DOI Direct Link |
Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors: kinetics of cytosolic OGT accumulation and nuclear translocation.
We have created a stable, tetracycline-inducible HeLa cell line that... | 15th April, 2004
| Hexos,
| Anal Biochem. 2003 Aug 15;319(2):304-13.
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Measurement of UDP-N-acetylglucosaminyl transferase (OGT) in brain cytosol and characterization of anti-OGT antibodies.
UDP-N-acetylglucosaminyl transferase (OGT) catalyzes O-linked... | 31st January, 2004
| Hexos, Inc., 18304 NE 153rd Street, Woodinville, WA 98072, USA.
| Anal Biochem. 2003 Mar 15;314(2):169-79.
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UDP-N-acetylglucosaminyl transferase (OGT) in brain tissue: temperature sensitivity and subcellular distribution of cytosolic and nuclear enzyme.
In brain tissue, UDP-N-acetylglucosaminyl transferase (OGT) is known to... | 13th November, 2003
| Hexos, Inc., 18304 NE 153rd Street, Woodinville, WA 98072, USA.
| J Neurochem. 2003 Sep;86(5):1271-80.
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