Huntingdon Life Sciences provides a comprehensive range of pre-clinical safety testing for Pharmaceuticals and Biopharmaceuticals. With facilities at Huntingdon and Eye in the UK and Princeton, New Jersey in the USA we have 1,300 staff world-wide and nearly fifty years of experience in the design and implementation of testing programmes.
Services: Immunology / Immunotoxicology, Pharmacology, General Toxicology / Specialised Pathology, Metabolism, pharmacokinetics and bioanalysis, Pharmaceutical analysis and stability testing, Programme Management, Central Laboratory Service.
Huntingdon Life Sciences can also manage your early clinical programmes and identify phase I units most appropriate to meet your drugs requirements.
| Contact Details: |
| Woolley Road, Alconbury |
| Huntingdon |
| Cambridgeshire |
| PE28 4HS |
| United Kingdom |
| Tel: | +44 (0) 1480 892000 |
| Fax: | +44 (0) 1480 892205 |
| Email: | |
| WWW: | www.huntingdon.com/
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Recent Publications by Huntingdon Life Sciences Limited: |  |
An analysis of the results from Two-Generation Reproduction Toxicity Studies to assess the value of mating animals of the second (F1) generation for the detection of adverse treatment-related effects on reproductive performance.
The need to routinely perform a two-generation study to assess... | 8th July, 2008
| Huntingdon Life Sciences, Eye, Suffolk IP23 7PX, UK.
| Reprod Toxicol. 2008 Sep;26(1):47-50. Epub 2008 Jun 18.
DOI Direct Link |
Monoclonal antibody first dose cytokine release syndromes-mechanisms and prediction.
Acute cytokine release syndromes are associated with some therapeutic... | 3rd April, 2008
| Huntingdon Life Sciences Ltd, Huntingdon, United Kingdom.
| J Immunotoxicol. 2008 Jan;5(1):11-5.
DOI Direct Link |
An impaired breeding phenotype in mice with a genetic deletion of beta-2 microglobulin and diminished MHC class I expression: role in reproductive fitness.
Beta-2 microglobulin (B2M) plays a pivotal role in the biology of mammals,... | 26th September, 2007
| Department of Experimental Biology, Huntingdon Life Sciences Ltd.,
| Biol Reprod. 2007 Aug;77(2):274-9. Epub 2007 Apr 18.
DOI Direct Link |
Pharmacokinetics and metabolism of the prodrug DB289 (2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) in rat and monkey and its conversion to the antiprotozoal/antifungal drug DB75 (2,5-bis(4-guanylphenyl)furan dihydrochloride).
DB289 (pafuramidine maleate; 2,5-bis[4-(N-methoxyamidino)phenyl]furan... | 6th September, 2007
| Department of Drug Metabolism, Huntingdon Life Sciences Ltd., Alconbury,
| Drug Metab Dispos. 2007 Jun;35(6):955-67. Epub 2007 Mar 14.
DOI Direct Link |
Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup.
As part of the Fourth International Workshop on Genotoxicity Testing... | 9th March, 2007
| Huntingdon Life Sciences, Cellular & Molecular Toxicology, Woolley Road,
| Mutat Res. 2007 Feb 3;627(1):31-5. Epub 2006 Nov 22.
DOI Direct Link |
→View more Huntingdon Life Sciences Limited research publications. |
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