Recent Publications by DiscoveRx Corporation: |
Rapid, antibody-free detection of recombinant proteins on blots using enzyme fragment complementation.
Alternative, antibody-free techniques to western analysis of protein blots... | 26th June, 2009
| DiscoveRx Corporation, 42501 Albrae St., Fremont, CA, 94538, USA.
| Methods Mol Biol. 2009;536:395-405.
DOI Direct Link |
A novel chemiluminescent substrate for detecting lactamase.
Beta-lactamase is a well established reporter for monitoring cellular... | 5th October, 2007
| DiscoveRx Corporation, 42501 Albrae Street, Fremont, CA 94538, USA.
| Mol Biosyst. 2007 Jun;3(6):431-8. Epub 2007 May 1.
DOI Direct Link |
Beta galactosidase complementation: a cell-based luminescent assay platform for drug discovery.
Many cell-based assays interrogating cell pathway activation employ... | 25th April, 2007
| DiscoveRx Corp., Fremont, CA, USA.
| Assay Drug Dev Technol. 2007 Feb;5(1):137-44.
DOI Direct Link |
Muscarinic receptor subtypes in neuronal and non-neuronal cholinergic function.
1 Muscarinic M1-M5 receptors mediate the metabotropic actions of... | 15th November, 2006
| DiscoveRx Corp, 42501, Albrae St., Suite 100, Fremont, CA 94538, USA.
| Auton Autacoid Pharmacol. 2006 Jul;26(3):219-33.
DOI Direct Link |
A homogeneous cell-based assay to measure nuclear translocation using beta-galactosidase enzyme fragment complementation.
Positional complementation describes the use of homogeneous assays using... | 6th September, 2006
| DiscoveRx Corp., Fremont, CA 94538, USA.
| Assay Drug Dev Technol. 2006 Jun;4(3):263-72.
DOI Direct Link |
A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5'-diphosphate accumulation.
The authors describe an assay to measure the generation of adenosine... | 26th August, 2006
| DiscoveRx Corporation, Fremont, California 94538, USA.
| J Biomol Screen. 2006 Jun;11(4):390-9. Epub 2006 Apr 28.
DOI Direct Link |
Antibody-free method for protein detection on blots using enzyme fragment complementation.
The authors describe an assay to measure the generation of adenosine... | 28th April, 2006
| DiscoveRx Corporation, Fremont, CA 94538, USA.
| Biotechniques. 2006 Mar;40(3):381-3.
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Emerging concepts in GPCR function--the influence of cell phenotype on GPCR pharmacology.
G protein coupled receptors (GPCRs) are an important class of... | 1st February, 2006
| DiscoveRx Corp, 42501 Albrae St., Fremont, CA 94538, USA.
| Proc West Pharmacol Soc. 2005;48:31-4.
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Muscarinic receptor subtype pharmacology and physiology.
Screening technologies for G protein-coupled receptors comprise two major... | 15th November, 2005
| DiscoveRx Corporation, Albrae Street, Fremont, CA 94538, USA.
| Prog Med Chem. 2005;43:105-36.
DOI Direct Link |
Functional G protein-coupled receptor assays for primary and secondary screening.
Screening technologies for G protein-coupled receptors comprise two major... | 5th October, 2005
| DiscoveRx Corp., 42501 Albrae St., Fremont, CA 94358, USA.
| Comb Chem High Throughput Screen. 2005 Jun;8(4):311-8.
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High-throughput screening using label-free technologies.
Screening technologies for G protein-coupled receptors comprise two major... | 30th March, 2005
| DiscoveRx Corp., Fremont, CA, USA.
| J Biomol Screen. 2004 Sep;9(6):465-6.
DOI Direct Link |
Beta galactosidase enzyme fragment complementation as a high-throughput screening protease technology.
The authors describe a homogeneous, high-throughput screening (HTS) assay... | 16th March, 2005
| DiscoveRx Corp., 42501, Albrae Street, Suite 100, Fremont, CA 94538, USA.
| J Biomol Screen. 2004 Aug;9(5):398-408.
DOI Direct Link |
Homogeneous assays for cellular protein degradation using beta-galactosidase complementation: NF-kappaB/IkappaB pathway signaling.
Activation of cells by the tumor necrosis factor-alpha (TNF-alpha) and... | 17th November, 2004
| DiscoveRx Corp., Fremont, CA 94538, USA.
| Assay Drug Dev Technol. 2003 Dec;1(6):823-33.
DOI Direct Link |
Enzyme fragment complementation: a flexible high throughput screening assay technology.
High-affinity complementation of a small fragment of beta-galactosidase to... | 20th May, 2004
| DiscoveRx Corporation,
| Assay Drug Dev Technol. 2002 Nov;1(1 Pt 1):97-104.
DOI Direct Link |
A high-throughput, nonisotopic, competitive binding assay for kinases using nonselective inhibitor probes (ED-NSIP).
A novel competitive binding assay for protein kinase inhibitors has been... | 12th December, 2003
| DiscoveRx Corporation, Fremont, CA, USA.
| J Biomol Screen. 2002 Dec;7(6):507-14.
DOI Direct Link |
