Gentest Corporation

Contact Details: MA United States of America Tel: 617 935 5115 Fax: 617 938 8644 Email:

Recent Publications by Gentest Corporation:
Differential time- and NADPH-dependent inhibition of CYP2C19 by enantiomers of fluoxetine. Fluoxetine [+/--N-methyl-3-phenyl-3-[(alpha, alpha,...	15th July, 2009	BD Biosciences, BD Gentest Contract Research Services, 6 Henshaw Street,	Drug Metab Dispos. 2009 Apr;37(4):695-8. Epub 2009 Jan 14. DOI Direct Link
Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design. 1. Recent guidance from the US Food and Drug Administration (USFDA) has...	25th June, 2009	BD Biosciences Discovery Labware, BD Gentest Contract Research Services,	Xenobiotica. 2009 Feb;39(2):99-112. DOI Direct Link
Determination of CYP4A11-catalyzed lauric acid 12-hydroxylation by high-performance liquid chromatography with radiometric detection. Fluoxetine [+/--N-methyl-3-phenyl-3-[(alpha, alpha,...	12th December, 2003	GENTEST Corporation, Woburn, MA, USA.	Methods Mol Biol. 1998;107:163-7. DOI Direct Link
CYP2D6-dependent bufuralol 1'-hydroxylation assayed by reversed-phase ion-pair high-performance liquid chromatography with fluorescence detection. Fluoxetine [+/--N-methyl-3-phenyl-3-[(alpha, alpha,...	12th December, 2003	GENTEST Corporation, Woburn, MA, USA.	Methods Mol Biol. 1998;107:141-5. DOI Direct Link
CYP2C19-mediated (S)-mephenytoin 4'-hydroxylation assayed by high-performance liquid chromatography with radiometric detection. Fluoxetine [+/--N-methyl-3-phenyl-3-[(alpha, alpha,...	12th December, 2003	GENTEST Corporation, Woburn, MA, USA.	Methods Mol Biol. 1998;107:135-9. DOI Direct Link
→View more Gentest Corporation research publications.

Gentest Corporation Patents:
US Patent No.	Title
6420131	Use of fluorescein aryl ethers in high throughput cytochrome P450 inhibition assays
6207404	Coumarin-based CYP3A fluorescent assay reagents
6130342	CYP2D fluorescent assay reagents
5726041	Method for detecting a receptor-ligand complex using a cytochrome P450 reporter gene
5429948	Human cell line stably expressing 5cDNAS encoding procarcinogen-activating enzymes and related mutagenicity assays
→View more Gentest Corporation patents.

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