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Immunomedics

Immunomedics is a New Jersey-based biopharmaceutical company focused on the development of monoclonal, antibody-based products for the targeted treatment of cancer, autoimmune and other serious diseases. We have developed a number of advanced proprietary technologies that allow us to create humanized antibodies that can be used either alone in unlabeled or “naked” form, or conjugated with radioactive isotopes, chemotherapeutics or toxins, in each case to create highly targeted agents. Using these technologies, we have built a pipeline of therapeutic product candidates that utilize several different mechanisms of action. We have recently licensed our lead product candidate, epratuzumab, to UCB, S.A. for the treatment of all autoimmune disease indications worldwide. We have retained the rights for epratuzumab in oncology indications for which UCB has been granted a buy-in option. UCB has development, manufacture and commercialization rights, and is responsible for all clinical trials evaluating epratuzumab for the treatment of patients with moderate and severe lupus. At present, there is no cure for lupus and no new lupus drug has been approved in the U.S. in the last 40 years. We believe that our portfolio of intellectual property, which includes approximately 108 patents issued in the United States, and more than 250 other issued patents worldwide, protects our product candidates and technologies. We also have a majority ownership in IBC Pharmaceuticals, Inc., which is developing a novel dock and lock methodology, and a new method of delivering imaging and therapeutic agents selectively to disease, especially different solid cancers (colorectal, lung, pancreas, etc.), by proprietary, antibody-based, pretargeting methods. We have transitioned our focus away from the development of diagnostic imaging products in order to accelerate the development of our therapeutic product candidates. Consistent with our de-emphasis on our diagnostic business, we no longer commercialize CEA-Scan®. LeukoScan® will continue to be manufactured and commercialized by us in territories where regulatory approvals have been granted. Furthermore, as of June 30, 2006, research and development into diagnostic product candidates was no longer a material portion of our business.


Contact Details:
300 American Road
Morris Plains
NJ
07950
United States of America
Tel:973 605 8200
Fax:973 605 8282
Email:info@immunomedics.com
WWW:

www.immunomedics.com/




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Recent Publications by Immunomedics:

CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates.
PURPOSE: To improve the efficacy and reduce the gastrointestinal toxicity...
1st October, 2009
Immunomedics, Inc., Morris Plains, New Jersey 07950, USA. Clin Cancer Res. 2009 Oct 1;15(19):6052-61. Epub 2009 Sep 29.
DOI Direct Link
A New Method to Produce MonoPEGylated Dimeric Cytokines Shown with Human Interferon-alpha2b.
We have adapted the dock-and-lock (DNL) method into a novel PEGylation...
10th September, 2009
IBC Pharmaceuticals, Inc., Morris Plains, New Jersey 07950, Immunomedics, Bioconjug Chem. 2009 Sep 8.
DOI Direct Link
CD20-targeted tetrameric interferon-alpha, a novel and potent immunocytokine for the therapy of B-cell lymphomas.
Interferon-alpha (IFN-alpha) has direct inhibitory effects on some tumors...
28th August, 2009
Immunomedics Inc, Blood. 2009 Oct 29;114(18):3864-71. Epub 2009 Aug 26.
DOI Direct Link
A novel method of 18F radiolabeling for PET.
Small biomolecules are typically radiolabeled with (18)F by binding it to...
22nd July, 2009
Immunomedics, Inc., 300 American Way, Morris Plains, NJ 07950, USA. J Nucl Med. 2009 Jun;50(6):991-8. Epub 2009 May 14.
DOI Direct Link
Hexavalent bispecific antibodies represent a new class of anticancer therapeutics: 1. Properties of anti-CD20/CD22 antibodies in lymphoma.
The dock and lock (DNL) method is a new technology for generating...
17th July, 2009
IBC Pharmaceuticals, Blood. 2009 Jun 11;113(24):6161-71. Epub 2009 Apr 16.
DOI Direct Link

View more Immunomedics research publications.

Press Releases on Immunomedics:

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New Options for Treatment of RA and Lupus are Focus of Rheumatology Thought Leader Panel 6th November, 2009 MedPredict
-- Role of other mechanisms, including CTLA4, IL-6, IL-17, JAK, Syk, TNF/PDE4, BTK, MEK, and S1P. Companies/Partnerships mentioned in this report include: Abbott, Alder, Amgen/Pfizer,
Reportlinker Adds Monoclonal Antibody Therapies 2007: Competitive Landscape and Pipeline Insight 5th November, 2009 Reportlinker
NEW YORK, Nov. 5 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Monoclonal Antibody Therapies 2007: Competitive Landscape and Pipeline
Reportlinker Adds Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment 26th October, 2009 Reportlinker
-- A focus on "engineered" antibodies Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment reviews the broad drug development effort that is focused on bringing
New Report Just Published: World Prostate Cancer Therapeutics Market Report 7th July, 2009 Reportlinker
NEW YORK, July 7 /PRNewswire/ -- Reportlinker.com just added a new market research report to its catalogue. World Prostate Cancer Therapeutics Market http://www.reportlinker.com/p0119471/World
Two Targeted Therapies Likely Better Than One in Patients with Aggressive Lymphoma, Mayo Clinic Researchers Say 18th May, 2009 Mayo Clinic
ORLANDO, Fla., May 18 /PRNewswire-USNewswire/ -- When combined with a cocktail of chemotherapy drugs, two monoclonal antibodies, instead of one, appear to offer superior results in patients with

BioNews Results for Immunomedics:

Immunomedics Announces First Quarter Fiscal 2010 Results and Clinical Program Developments
Pharmacy Choice:  Nov 7 2009 12:22AM Matching: immunomedics
Immunomedics Announces First Quarter Fiscal 2010 Results and Clinical Program Developments
Individual.com:  Nov 6 2009 2:19PM Matching: immunomedics
Immunomedics Receives Corporate Award From New Jersey Inventors Hall of Fame
Therapeutics Daily:  Oct 23 2009 2:50PM Matching: immunomedics
xtremepicks.com: www.Xtremepicks.Com: Xtremepicks Alerts October 23, 2009 : IMMU, ANCI, SLTC and PCLN
Individual.com:  Oct 23 2009 5:55PM Matching: immunomedics
NIH Awards 3 Grants To Immunomedics
Individual.com:  Oct 21 2009 2:15PM Matching: immunomedics
Promote your company here: BioNewsCast - Press Release Distribution

View more Immunomedics news.

Immunomedics Clinical Trials:

Study of Epratuzumab (hLL2) in Patients With Waldenstrom's Macroglobulinemia

Immunomedics Patents:

US Patent No.Title
7033572 Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
7238785 RS7 antibodies
7238786 Monoclonal antibody cPAM4
7259249 Method for preparing conjugates of proteins and chelating agents
7282567 Monoclonal antibody hPAM4

View more Immunomedics patents.

Immunomedics (IMMU) Financial information Links from Barchart

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