Recent Publications by Immunomedics: |
A T-flask based screening platform for evaluating and identifying plant hydrolysates for a fed-batch cell culture process.
This paper presents a T-flask based screening platform for evaluating and... | 13th November, 2008
| Immunomedics, Inc., 300 American Road, Morris Plains, NJ, 07950, USA,
| Cytotechnology. 2007 Sep;55(1):15-29. Epub 2007 Aug 18.
DOI Direct Link |
Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy.
CPT-11 is a clinically used cancer drug, and it is a prodrug of the potent... | 23rd October, 2008
| Immunomedics, Inc., Morris Plains, New Jersey 07950, USA.
| J Med Chem. 2008 Nov 13;51(21):6916-26. Epub 2008 Oct 22.
DOI Direct Link |
Bispecific anti-CD20/22 antibodies inhibit B-cell lymphoma proliferation by a unique mechanism of action.
Combination immunotherapy with anti-CD20 and anti-CD22 mAbs shows... | 22nd May, 2008
| Immunomedics, Morris Plains, NJ, USA.
| Blood. 2008 Feb 15;111(4):2211-9. Epub 2007 Nov 19.
DOI Direct Link |
The dock and lock method: a novel platform technology for building multivalent, multifunctional structures of defined composition with retained bioactivity.
The idea, approach, and proof-of-concept of the dock and lock (DNL)... | 15th December, 2007
| Immunomedics, Inc.,
| Clin Cancer Res. 2007 Sep 15;13(18 Pt 2):5586s-5591s.
DOI Direct Link |
Fed-batch bioreactor process scale-up from 3-L to 2,500-L scale for monoclonal antibody production from cell culture.
This case study focuses on the scale-up of a Sp2/0 mouse myeloma cell line... | 20th October, 2007
| Immunomedics, Inc. 300 American Road, Morris Plains, New Jersey 07950,
| Biotechnol Bioeng. 2007 Sep 1;98(1):141-54.
DOI Direct Link |
Bispecific antibody pretargeting PET (immunoPET) with an 124I-labeled hapten-peptide.
We previously described a highly flexible bispecific antibody (bs-mAb)... | 23rd December, 2006
| Immunomedics, Inc., Morris Plains, New Jersey, USA.
| J Nucl Med. 2006 Oct;47(10):1678-88.
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Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/anti-CD74 humanized IgG4 antibody immunotoxin.
Ranpirnase (Rap) is a cytotoxic ribonuclease (RNase) isolated from frog... | 7th January, 2006
| Immunomedics, Morris Plains, NJ, USA.
| Blood. 2005 Dec 15;106(13):4308-14. Epub 2005 Aug 18.
DOI Direct Link |
Ligand-targeted liposomes for cancer treatment.
Selective targeting of ligand-targeted liposomes containing anticancer... | 16th December, 2005
| Immunomedics, Inc., Morris Plains, NJ 07940, USA.
| Curr Drug Deliv. 2005 Oct;2(4):369-81.
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Deferoxamine as a chelator for 67Ga in the preparation of antibody conjugates.
(67)Ga antibodies (Abs) have been shown to be effective agents for... | 13th December, 2005
| Immunomedics, Inc., Morris Plains, NJ 07950, USA.
| Nucl Med Biol. 2005 Jul;32(5):513-9.
DOI Direct Link |
Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys.
PURPOSE: IMMU-110 is a drug immunoconjugate composed of doxorubicin... | 8th November, 2005
| Immunomedics, Inc., Morris Plains, New Jersey 07950, USA.
| Clin Cancer Res. 2005 Jul 15;11(14):5257-64.
DOI Direct Link |
Cancer therapy with radiolabeled and drug/toxin-conjugated antibodies.
Radioimmunotherapy and antibody-directed chemotherapy have emerged as... | 12th October, 2005
| Immunomedics, Inc., 300 American Road, Morris Plains, NJ 07950, USA.
| Technol Cancer Res Treat. 2005 Aug;4(4):375-91.
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Development of humanized antibodies as cancer therapeutics.
Recent success in the development of monoclonal antibody-based anti-cancer... | 17th August, 2005
| Immunomedics,
| Methods. 2005 May;36(1):84-95.
DOI Direct Link |
Advantage of a residualizing iodine radiolabel in the therapy of a colon cancer xenograft targeted with an anticarcinoembryonic antigen monoclonal antibody.
PURPOSE: A disadvantage of conventionally radioiodinated monoclonal... | 9th August, 2005
| Garden State Cancer Center, Center for Molecular Medicine and Immunology,
| Clin Cancer Res. 2005 Apr 1;11(7):2727-34.
DOI Direct Link |
Clinical-scale radiolabeling of a humanized anticarcinoembryonic antigen monoclonal antibody, hMN-14, with residualizing 131I for use in radioimmunotherapy.
Radiolabeling of monoclonal antibodies (mAbs) with an intracellularly... | 30th March, 2005
| Immunomedics, Inc., 300 American Rd., Morris Plains, NJ 07950, USA.
| J Nucl Med. 2005 Jan;46(1):153-9.
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Monoclonal Antibodies in Cancer--Fourth International Congress. 3-6 September 2004, Colorado Springs, CO, USA.
Radiolabeling of monoclonal antibodies (mAbs) with an intracellularly... | 30th March, 2005
| Immunomedics Inc, 300 American Road, Morris Plains, NJ 07950, USA.
| IDrugs. 2004 Nov;7(11):971-3.
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