Recent Publications by GenVec: |
Differential specificity and immunogenicity of adenovirus 5 neutralizing antibodies elicited by natural infection or immunization.
A recent clinical trial of a T-cell-based AIDS vaccine delivered with... | 23rd October, 2009
| Vaccine Research Center, NIAID, National Institutes of Health, Bldg. 40,
| J Virol. 2009 Oct 21.
DOI Direct Link |
Combination of human tumor necrosis factor-alpha (hTNF-alpha) gene delivery with gemcitabine is effective in models of pancreatic cancer.
Pancreatic adenocarcinoma is an aggressive and highly lethal malignancy.... | 16th May, 2009
| Department of Research, GenVec Inc, Gaithersburg, MD 20878, USA.
| Cancer Gene Ther. 2009 Nov;16(11):841-7. Epub 2009 May 15.
DOI Direct Link |
Alternate serotype adenovector provides long-term therapeutic gene expression in the eye.
PURPOSE: To determine whether the duration of transgene expression from an... | 2nd April, 2009
| Pre-Clinical Sciences, GenVec Inc, Gaithersburg, MD 20878, USA.
| Mol Vis. 2008;14:2535-46. Epub 2008 Dec 30.
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Repeat administration of proteins to the eye with a single intraocular injection of an adenovirus vector.
Delivery of therapeutic proteins, such as antiangiogenic proteins, to the... | 23rd January, 2009
| Vector Sciences, GenVec, Inc., Gaithersburg, Maryland, USA.
| Mol Ther. 2008 Aug;16(8):1444-9. Epub 2008 Jun 10.
DOI Direct Link |
Persistent expression of PEDF in the eye using high-capacity adenovectors.
Ocular neovascularization, the growth of abnormal blood vessels in the... | 8th January, 2009
| GenVec, Inc. Research Department, Gaithersburg, Maryland 20878, USA.
| Mol Ther. 2008 Dec;16(12):1986-94. Epub 2008 Sep 30.
DOI Direct Link |
Promoters influence the kinetics of transgene expression following adenovector gene delivery.
BACKGROUND: The kinetics of gene expression from adenovirus-based delivery... | 19th April, 2008
| GenVec, Inc., 65 West Watkins Mill Road, Gaithersburg, MD 20878, USA.
| J Gene Med. 2008 Feb;10(2):123-31.
DOI Direct Link |
Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response.
TNFerade is a replication incompetent adenovector designed to express... | 4th January, 2008
| GenVec, Inc., 65 W. Watkins Mill Road, Gaithersburg, MD 20878, USA.
| Clin Exp Metastasis. 2007;24(7):521-31. Epub 2007 Jul 25.
DOI Direct Link |
Experimental treatment of ovarian cancers by adenovirus vectors combining receptor targeting and selective expression of tumor necrosis factor.
Ovarian cancer is the fourth most common cancer among women and existing... | 9th November, 2007
| GenVec Inc, Gaithersburg, Gaithersburg, MD 20878, USA.
| Int J Oncol. 2007 Oct;31(4):813-22.
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Rescue and production of vaccine and therapeutic adenovirus vectors expressing inhibitory transgenes.
Expression of certain transgenes from an adenovirus vector can be... | 18th September, 2007
| GenVec, Inc. 65 West Watkins Mill Rd, Gaithersburg MD 20878, USA.
| Mol Biotechnol. 2007 Mar;35(3):263-73.
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Comprehensive characterization of the 293-ORF6 cell line.
Expression of certain transgenes from an adenovirus vector can be... | 4th May, 2006
| GenVec, Inc.,
| Dev Biol (Basel). 2006;123:225-33; discussion 265-6.
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Adenovector pigment epithelium-derived factor (AdPEDF) delivery for wet age-related macular degeneration.
PURPOSE: To determine whether repeat administration of an adenovector (Ad)... | 2nd March, 2006
| Preclinical Sciences in the Department of Research at GenVec, Inc.
| Retina. 2005 Dec;25(8 Suppl):S48-S49.
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Repeated administration of adenovector in the eye results in efficient gene delivery.
PURPOSE: To determine whether repeat administration of an adenovector (Ad)... | 10th February, 2006
| GenVec, Inc., Gaithersburg, Maryland 20878, USA.
| Invest Ophthalmol Vis Sci. 2006 Jan;47(1):299-305.
DOI Direct Link |
Adenovirus vector library: an approach to the discovery of gene and protein function.
A method was developed to generate a complex cDNA expression library... | 21st January, 2004
| GenVec Inc., 65 West Watkins Mill Road, Gaithersburg, MD 20878, USA.
| J Gen Virol. 2003 Dec;84(Pt 12):3417-22.
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VEGF gene therapy for coronary artery disease and peripheral vascular disease.
Coronary artery disease (CAD) and peripheral arterial disease (PAD) are... | 23rd August, 2003
| GenVec Inc., 65 West Watkins Mill Road, Gaithersburg, MD 20878, USA.
| Cardiovasc Radiat Med. 2002 Apr-Jun;3(2):114-7.
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Ligand-directed targeting of genes to the site of disease.
Coronary artery disease (CAD) and peripheral arterial disease (PAD) are... | 19th March, 2003
| GenVec, Inc.,
| Nat Med. 2003 Jan;9(1):135-9.
DOI Direct Link |
