Free radical and oxidant-mediated diseases.
Recent Publications by Inotek Corporation: |  |
Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c]isoquinolin- 5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one.
[reaction: see text] The synthesis of... | 10th February, 2006
| Inotek Pharmaceuticals Corporation, 100 Cummings Center, Beverly,
| Org Lett. 2005 Apr 28;7(9):1753-6.
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Mechanisms of cell necrosis.
Amiloride-sensitive, epithelial Na(+) channel (ENaC)-mediated, active... | 19th January, 2006
| Inotek Pharmaceuticals Corporation, Beverly, MA, USA.
| Crit Care Med. 2005 Dec;33(12 Suppl):S530-4.
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Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.
Activation of poly(ADP-ribose) polymerase (PARP) is an important factor in... | 13th January, 2006
| Inotek Pharmaceuticals Corporation, Beverly, Massachusetts, USA.
| J Pharmacol Exp Ther. 2005 Nov;315(2):812-20. Epub 2005 Aug 3.
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Cytokines stimulate expression of inducible nitric oxide synthase in DLD-1 human adenocarcinoma cells by activating poly(A) polymerase.
OBJECTIVE: The stimulation of epithelial cells by cytokines or... | 3rd November, 2005
| Inotek Pharmaceuticals Corporation, 100 Cummings Center, Suite 419E,
| Inflamm Res. 2004 Nov;53(11):604-8.
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Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.
Angiotensin II (AII) contributes to the pathogenesis of many... | 20th October, 2005
| Inotek Pharmaceuticals Corporation, Suite 419E, 100 Cummings Center,
| Mol Med. 2004 Jan-Jun;10(1-6):28-35.
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