Alteon Incorporated

Alteon is engaged in the discovery and development of pharmaceutical products for the treatment of the complications of diabetes and age-related diseases. Alteon's efforts have focused primarily on developing its lead first-in-class compound, pimagedine, as an agent to inhibit or block abnormal glucose/protein complexes, known as Advanced Glycosylation End-products ("A.G.E.s"), that lead to diabetic complications such as kidney disease and retinopathy. Alteon has completed certain clinical trials of pimagedine and is currently evaluating its future development.

Contact Details: 170 Williams Drive Ramsey NJ 07446 United States of America Tel: 201 934 5000 Fax: 201 934 8880 Email: nregan@alteonpharma.com WWW: www.alteon.com/

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Recent Publications by Alteon Incorporated:
Therapeutic potential of breakers of advanced glycation end product-protein crosslinks. Long-lived structural proteins, collagen and elastin, undergo continual...	12th December, 2003	Alteon Inc., 170 Williams	Arch Biochem Biophys. 2003 Nov 1;419(1):89-96.

Alteon Incorporated Patents:
US Patent No.	Title
5326779	Method of inhibiting the advanced glycosylation of proteins using 1,2-disubstituted-benzimidazoles
5698563	Bis-[hydrazones]
5744318	Monoclonal antibody for the detection of advanced glycosylation endproducts in biological samples
5766590	Therapeutic methods and pharmaceutical compositions
5850840	Methods for measurement and treatment predicated on the presence of advanced glycosylation endproducts in tobacco and its combustion byproducts
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