Ligand Pharmaceuticals

Ligand is an emerging specialty pharmaceutical company that discovers, develops and markets innovative small molecule drugs to address critical, unmet medical needs. Ligand markets four oncology and dermatology products in the United States – ONTAK®, Targretin® capsules, Targretin® gel and Panretin® gel. Ligand launched its fifth product, AVINZA™, a treatment for chronic, moderate-to-severe pain, in the second quarter of this year. In addition, Ligand's network of major pharmaceutical partners is developing products for men's and women's hormone-related diseases, osteoporosis, metabolic disorders, and cardiovascular and inflammatory diseases. Ligand's robust R&D pipeline is based on the company's leadership in gene transcription technology.

Contact Details: 10275 Science Center Drive San Diego CA 92121-1117 United States of America Tel: 858 550 7500 Fax: 858 550 7506 Email: investors@ligand.com WWW: www.ligand.com/

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Recent Publications by Ligand Pharmaceuticals:
Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones. A novel oxachrysenone series (2) of nonsteroidal selective androgen...	10th July, 2008	Discovery Research, Ligand Pharmaceuticals Inc., 10275 Science Center	Bioorg Med Chem Lett. 2008 Jun 1;18(11):3431-5. Epub 2008 Apr 8. DOI Direct Link
A Tissue-Selective Nonsteroidal Progesterone Receptor Modulator: 7,9-Difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochrome no[3,4-f]quinoline. The progesterone receptor plays an important role in the female...	17th June, 2008	Discovery Research, Ligand Pharmaceuticals Inc., 10275 Science Center	J Med Chem. 2008 Jul 10;51(13):3696-9. Epub 2008 Jun 14. DOI Direct Link
LGD-5552, an antiinflammatory glucocorticoid receptor ligand with reduced side effects, in vivo. Treatment of inflammation is often accomplished through the use of...	11th June, 2008	Discovery Research, Ligand Pharmaceuticals, San Diego, California 92121,	Endocrinology. 2008 May;149(5):2080-9. Epub 2008 Jan 24. DOI Direct Link
Discovery of structurally diverse nonsteroidal SPRMs based on a screening hit, 1,2-dihydro-2,2,4-trimethyl-6-phenylquinolinone. Synthetic steroidal progestins and antiprogestins have been widely used...	10th June, 2008	Discovery Research, Ligand Pharmaceuticals Inc., 10275 Science Center	Curr Top Med Chem. 2008;8(9):766-80.
Recent developments in the discovery of selective glucocorticoid receptor modulators (SGRMs). Steroidal glucocorticoids are widely prescribed for the treatment of a...	10th June, 2008	Discovery Research, Ligand Pharmaceuticals, 10275 Science Center Drive,	Curr Top Med Chem. 2008;8(9):750-65.
→View more Ligand Pharmaceuticals research publications.

BioNews Results for Ligand Pharmaceuticals:
APS 2008: Balancing Access and Risk in Acute Pain Management	Medscape:  Jul 3 2008 4:20PM Matching: ligand pharmaceuticals
MDS Pharma Services Names Dr. Lori McDonald to Executive Leadership Team	Healthcare Sales & Marketing Network:  Jun 27 2008 4:09AM Matching: ligand pharmaceuticals
MDS Pharma Services Names Dr. Lori McDonald to Executive Leadership Team	Citybizlist:  Jun 26 2008 9:11PM Matching: ligand pharmaceuticals
MDS Pharma Services Names Dr. Lori McDonald to Executive Leadership Team	SmartBrief:  Jun 26 2008 5:16PM Matching: ligand pharmaceuticals
MDS Pharma Services Names Dr. Lori McDonald to	Citybizlist:  Jun 26 2008 5:13PM Matching: ligand pharmaceuticals
Promote your company here: BioNewsCast - Press Release Distribution	→View more Ligand Pharmaceuticals news.

Ligand Pharmaceuticals Patents:
US Patent No.	Title
6444668	Combination regimens using progesterone receptor modulators
6566372	Bicyclic androgen and progesterone receptor modulator compounds and methods
6576676	Means for the modulation of processes mediated by retinold receptors and compounds useful therefor
6583145	Thio-oxindole derivatives
6593493	RXR modulators with improved pharmacologic profile
→View more Ligand Pharmaceuticals patents.

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