Recent Publications by MedImmune: |
Development of a PIV-vectored RSV vaccine: Preclinical evaluation of safety, toxicity, and enhanced disease and initial clinical testing in healthy adults.
MEDI-534 is a bivalent live attenuated vaccine candidate against human... | 30th September, 2008
| MedImmune, 297 North Bernardo Avenue, Mountain View, CA 94043, United
| Vaccine. 2008 Sep 23.
DOI Direct Link |
IMVAMUNE, an attenuated modified vaccinia Ankara virus vaccine for smallpox infection.
Bavarian Nordic is developing IMVAMUNE, which is based on a live... | 25th September, 2008
| MedImmune Inc, 297 N Bernardo Ave, Mountain View, CA 94043, USA.
| Curr Opin Mol Ther. 2008 Aug;10(4):407-17.
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Type I interferon: potential therapeutic target for psoriasis?
BACKGROUND: Psoriasis is an immune-mediated disease characterized by... | 25th September, 2008
| MedImmune, Inc., Gaithersburg, Maryland, United States of America.
| PLoS ONE. 2008 Jul 16;3(7):e2737.
DOI Direct Link |
Molecular studies of temperature-sensitive replication of the cold-adapted B/Ann Arbor/1/66, the master donor virus for live attenuated influenza FluMist((R)) vaccines.
Cold-adapted (ca) B/Ann Arbor/1/66 is the master donor virus for influenza... | 23rd September, 2008
| MedImmune, 297 North Bernardo Avenue, Mountain View, CA 94043, USA.
| Virology. 2008 Sep 18.
DOI Direct Link |
Improved outcomes with home-based administration of palivizumab: results from the 2000-2004 palivizumab outcomes registry.
BACKGROUND:: Palivizumab Outcomes Registry data collected during 4 years... | 9th September, 2008
| From the *Schneider Children's Hospital, New Hyde Park, NY; daggerMedical
| Pediatr Infect Dis J. 2008 Oct;27(10):870-3.
DOI Direct Link |
Duration of protection provided by live attenuated influenza vaccine in children.
BACKGROUND: Reliable availability of influenza vaccine before October... | 9th September, 2008
| MedImmune, One MedImmune Way, Gaithersburg, MD 20878, USA.
| Pediatr Infect Dis J. 2008 Aug;27(8):744-8.
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The cold adapted and temperature sensitive influenza A/Ann Arbor/6/60 virus, the master donor virus for live attenuated influenza vaccines, has multiple defects in replication at the restrictive temperature.
We have previously determined that the temperature sensitive (ts) and... | 5th September, 2008
| MedImmune, 297 North Bernardo Avenue, Mountain View, CA 94043, USA.
| Virology. 2008 Sep 1.
DOI Direct Link |
Analysis of 90 Mb of the potato genome reveals conservation of gene structures and order with tomato but divergence in repetitive sequence composition.
BACKGROUND: The Solanaceae family contains a number of important crop... | 4th September, 2008
| Department of Plant Biology, Michigan State University, 166 Plant Biology
| BMC Genomics. 2008 Jun 13;9:286.
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Optimization of plasmid-only rescue of highly attenuated and temperature-sensitive respiratory syncytial virus (RSV) vaccine candidates for human trials.
Respiratory syncytial virus (RSV) is the most common cause of severe... | 30th August, 2008
| MedImmune, 297 N. Bernardo Avenue, Mountain View, CA 94043 USA.
| J Virol Methods. 2008 Sep 5.
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Avian Influenza H6 Viruses Productively Infect and Cause Illness in Mice and Ferrets.
Influenza pandemic preparedness has focused on influenza H5 and H7 subtype... | 22nd August, 2008
| Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD, USA 20892;
| J Virol. 2008 Aug 20.
DOI Direct Link |
Structural characterization of a human Fc fragment engineered for lack of effector functions.
The first three-dimensional structure of a human Fc fragment genetically... | 14th August, 2008
| Department of Antibody Discovery and Protein Engineering, MedImmune Inc.,
| Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):700-4. Epub 2008
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A novel method for determination of the affinity of protein: protein interactions in homogeneous assays.
Nonradioactive homogeneous assays are widely used to screen for inhibitors... | 16th July, 2008
| MedImmune Ltd. Milstein Building, Granta Park, Cambridge, UK CB1 6GH.
| J Biomol Screen. 2008 Aug;13(7):674-82. Epub 2008 Jul 14.
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The role of IL-21 in regulating B-cell function in health and disease.
SUMMARY: Interleukin-21 (IL-21) belongs to a family of cytokines that... | 11th July, 2008
| Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal
| Immunol Rev. 2008 Jun;223:60-86.
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Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters.
BACKGROUND: Human metapneumovirus (hMPV) infection can cause acute lower... | 4th July, 2008
| Research Dept, MedImmune, Mountain View, CA 94043, USA.
| Virol J. 2008 Jun 3;5:69.
DOI Direct Link |
From bench to cageside: Risk assessment for rodent pathogen contamination of cells and biologics.
Many newly developed animal models involve the transfer of cells, serum,... | 29th May, 2008
| MedImmune, One MedImmune Way, Gaithersburg, MD 20878, USA.
| ILAR J. 2008;49(3):310-5.
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