Recent Publications by MedImmune: |
Increased vagal airway tone in fatal asthma.
Slow-onset asthma deaths are characterized by eosinophilic airway... | 13th November, 2009
| MedImmune, LLC, Clinical Development, One MedImmune Way, Office # 45C20,
| Med Hypotheses. 2009 Nov 9.
DOI Direct Link |
Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors.
EphA2 is a receptor tyrosine kinase that has been shown to be... | 6th November, 2009
| MedImmune, Inc., Gaithersburg, MD 20878, USA.
| Neoplasia. 2009 Jun;11(6):509-17, 2 p following 517.
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Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years.
BACKGROUND: Human metapneumovirus (HMPV) is an important cause of acute... | 5th November, 2009
| Department of Pediatrics, Vanderbilt University School of Medicine,
| Virol J. 2009 Sep 9;6:138.
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The impact of continuous renal replacement therapy on drug therapy.
Critically ill patients with multisystem organ failure often require daily... | 5th November, 2009
| Medical Information, MedImmune, Inc., Frederick, Maryland, USA.
| Clin Pharmacol Ther. 2009 Nov;86(5):562-5. Epub 2009 Sep 2.
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Generation of live attenuated novel influenza A/California/7/09 (H1N1) vaccines with high yield in embryonated chicken eggs.
Several live attenuated influenza A/California/7/09 (H1N1) candidate... | 30th October, 2009
| MedImmune, 319 North Bernardo Ave, Mountain View, CA 94043.
| J Virol. 2009 Oct 28.
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The design and characterization of oligospecific antibodies for simultaneous targeting of multiple disease mediators.
Monoclonal antibodies are traditionally used to block the function of a... | 29th October, 2009
| Department of Antibody Discovery and Protein Engineering, MedImmune, One
| J Mol Biol. 2009 Oct 30;393(3):672-92. Epub 2009 Aug 20.
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Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus.
OBJECTIVE: Type I interferons (IFNs) play an important role in the... | 18th August, 2009
| MedImmune,
| Arthritis Rheum. 2009 Jun;60(6):1785-96.
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Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2-positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib.
IPI-504 is a novel, highly soluble small-molecule inhibitor of heat shock... | 13th August, 2009
| Department of Pre-Clinical Oncology, MedImmune, Gaithersburg, MD 20878,
| Mol Cancer Ther. 2009 Aug;8(8):2131-41. Epub 2009 Aug 11.
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GSK's novel split-virus adjuvanted vaccines for the prevention of the H5N1 strain of avian influenza infection.
Although influenza pandemics occur infrequently, they are unpredictable.... | 31st July, 2009
| MedImmune, Clinical Testing Laboratories, Mountain View, CA 94043, USA.
| Curr Opin Mol Ther. 2009 Jun;11(3):337-45.
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Tartrate-resistant acid phosphatase (TRACP 5b): a biomarker of bone resorption rate in support of drug development: modification, validation and application of the BoneTRAP kit assay.
A commercial kit assay of tartrate-resistant acid phosphatase (TRACP 5b)... | 30th July, 2009
| Pharmacokinetics and Drug Metabolism, Amgen Inc., Thousand Oaks, CA 91320,
| J Pharm Biomed Anal. 2009 Jul 12;49(5):1203-12. Epub 2009 Mar 20.
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Two first-in-human, open-label, phase I dose-escalation safety trials of MEDI-528, a monoclonal antibody against interleukin-9, in healthy adult volunteers.
BACKGROUND: Interleukin-9 (IL-9) is involved in pathogenic aspects of the... | 28th July, 2009
| Medlmmune, LLC, Gaithersburg,
| Clin Ther. 2009 Apr;31(4):728-40.
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Use of MDCK cells for production of live attenuated influenza vaccine.
To develop a cell-based live attenuated influenza vaccine (LAIV)... | 30th June, 2009
| MedImmune, LLC., 3055 Patrick Henry Drive, Santa Clara, CA 95054, United
| Vaccine. 2009 Oct 30;27(46):6460-3. Epub 2009 Jun 24.
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Challenges in developing a pediatric RSV vaccine.
RSV bronchiolitis is the leading cause of infant hospitalization in... | 27th June, 2009
| Research Department, MedImmune, Mountain View, CA, USA.
| Hum Vaccin. 2009 Sep;5(9):582-91. Epub 2009 Sep 28.
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Current status of live attenuated influenza vaccine in the United States for seasonal and pandemic influenza.
A live attenuated influenza vaccine (LAIV) is currently approved in the... | 9th June, 2009
| MedImmune, One MedImmune Way, Gaithersburg, MD 20878, USA.
| Influenza Other Respi Viruses. 2008 Nov;2(6):193-202.
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Phase-I study medi-534, of a live, attenuated intranasal vaccine against respiratory syncytial virus and parainfluenza-3 virus in seropositive children.
A live, attenuated respiratory syncytial virus and parainfluenza virus... | 2nd June, 2009
| From the *MedImmune, Gaithersburg, MD; and daggerUniversity Physicians
| Pediatr Infect Dis J. 2009 Jul;28(7):655-8.
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