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Microbiotix Incorporated

MICROBIOTIX is an emerging biotechnology/pharmaceutical company currently engaged in research and development of novel anti-infective drugs. The company maintains its corporate offices and research laboratories in the Massachusetts Biotechnology Research Park, located in Worcester, Massachusetts. Incorporated in August 1998, MICROBIOTIX is focusing on the development of a series of patented, antibacterial compounds to address the growing concern of antibiotic-resistant bacterial infections.


Contact Details:
One Innovation Drive
Worcester
MA
01605
United States of America
Tel:(508) 757-2800
Fax:(508) 757-1999
Email:
WWW:

www.mrst.gouv.qc.ca/




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Recent Publications by Microbiotix Incorporated:

A method to assay inhibitors of DNA polymerase IIIC activity.
The need for new drugs to treat infections caused by antibiotic-resistant...
23rd May, 2008
Microbiotix Inc., Worcester, MA, USA. Methods Mol Med. 2008;142:25-36.
DOI Direct Link
A high-throughput, homogeneous, bioluminescent assay for Pseudomonas aeruginosa gyrase inhibitors and other DNA-damaging agents.
A homogeneous, sensitive, cellular bioluminescent high-throughput screen...
19th December, 2007
Microbiotix, Inc., Worcester, Massachusetts 01605, USA. J Biomol Screen. 2007 Sep;12(6):855-64. Epub 2007 Jul 20.
DOI Direct Link
Antibacterial activity and mechanism of action of a novel anilinouracil-fluoroquinolone hybrid compound.
The anilinouracils (AUs) such as 6-(3-ethyl-4-methylanilino)uracil (EMAU)...
3rd July, 2007
Microbiotix, Inc., One Innovation Drive, Worcester, MA 01605, USA. Antimicrob Agents Chemother. 2007 Jan;51(1):119-27. Epub 2006 Oct 30.
DOI Direct Link
Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase.
The FabI-related enoyl-ACP reductase enzymes of bacteria meet many of the...
15th December, 2005
Microbiotix, Inc., One Innovation, Dr. Worcester, MA 01605, USA. Curr Drug Targets Infect Disord. 2005 Sep;5(3):297-305.
DNA gyrase and DNA topoisomerase of Bacillus subtilis: expression and characterization of recombinant enzymes encoded by the gyrA, gyrB and parC, parE genes.
Bacillus subtilis Bs gyrA and gyrB genes specifying the DNA gyrase...
18th March, 2004
Microbiotix, Inc., One Innovation Drive, Worcester, MA 01605, USA. Protein Expr Purif. 2003 Jun;29(2):259-64.

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