Over the past quarter century, Amgen has pioneered the methods by which human proteins that play a role in disease processes are identified, isolated, produced in quantity and used as therapeutics. Today, Amgenhas research programs in inflammation, metabolic disorders and osteoporosis, neurology, oncology and hematology. The company has R&D facilities in Thousand Oaks, CA; San Francisco, CA; Cambridge, MA; Cambridge, UK; Regensburg, Germany; and Seattle, WA.
With expertise in proteins, small molecules, antibodies, peptibodies, and nucleic acids, Amgen’s scientists can pursue the study of disease, choose the best target for a disease and then use the modality most likely to have an effect on that target. This approach positions Amgen as one of the only companies with capabilities across a range of modalities.
Mastering the tools of therapeutic development, as they emerge, is crucial to Amgen’s ongoing success. Accordingly, the company has invested at least 20 percent of product sales in research and development each year since 1994—a total of approximately $2.0 billion in 2004.
| Contact Details: |
| One Amgen Center Drive |
| Thousand Oaks |
| CA |
| 91320 1799 |
| United States of America |
| Tel: | 805 447 1000 |
| Fax: | 805 447 1010 |
| Email: | |
| WWW: | www.amgen.com/
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Recent Publications by Amgen Incorporated: |  |
[Hemoglobin variability in chronic renal failure patients.]
In recent years, the question of hemoglobin (Hb) stability in patients... | 10th October, 2008
| Amgen Kft. Orvostudomanyi Osztaly Budapest Szabadsag ter 7. 1054.
| Orv Hetil. 2008 Oct 12;149(41):1925-34.
DOI Direct Link |
Impact of elevated C-reactive protein levels on erythropoiesis-stimulating agent (ESA) dose and responsiveness in hemodialysis patients.
BACKGROUND: Inflammation in an ESRD patient may impact responsiveness to... | 9th October, 2008
| 1Department of Biostatistics and Epidemiology, Amgen Inc., Thousand Oaks,
| Nephrol Dial Transplant. 2008 Oct 7.
DOI Direct Link |
Supercritical fluid chromatography comparison of the poly(trans-1,2-cyclohexanediyl-bis acrylamide) (P-CAP) column with several derivatized polysaccharide-based stationary phases.
The poly(trans-1,2-cyclohexanediyl-bis acrylamide) (P-CAP) column has so... | 8th October, 2008
| Discovery Analytical Sciences, Molecular Structure, Chemistry Research and
| J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 16.
DOI Direct Link |
Chemical Reactivity of Methoxy 4-O-Aryl Quinolines: Identifcation of Glutathione Displacement Products in Vitro and in Vivo.
AMG 458 {1-(2-hydroxy-2-methylpropyl)-... | 8th October, 2008
| Pharmacokinetics and Drug Metabolism and Medicinal Chemistry, Amgen, Inc.,
| Chem Res Toxicol. 2008 Oct 7.
DOI Direct Link |
Re-estimating the sample size of an on-going blinded trial based on the method of randomization block sums.
We extend a method we had previously described (Statist. Med. 2005) to... | 7th October, 2008
| Amgen Inc., 1120 Veterans Blvd., South San Francisco, CA 94080, U.S.A.
| Stat Med. 2008 Oct 6.
DOI Direct Link |
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