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MitoKorMitoKor is Pioneering Mitochondrial Medicine™ by developing therapeutic solutions for diseases, based on mitochondrial research. Mitochondria are the self-charging batteries of cells, driving energy production, metabolism, and cellular life and death, as well as participating in other key signaling pathways. Mitochondria also house the "other" human genome, inherited only from the mother. Mitochondrial dysfunction is a significant contributing factor in the pathophysiology of major diseases such as Alzheimer's and Parkinson's diseases, osteoarthritis, and type 2 diabetes mellitus. MitoKor and its wholly-owned subsidiaries, Mimotopes and Apollo BioPharmaceutics, have established core competencies in biotechnology, combinatorial drug discovery, target discovery, assay and diagnostic development, as well as in mitochondrial and nuclear proteomics and genomics, disease modeling and pharmacogenomics.
MitoKor is headquartered in San Diego, California, with satellite facilities in Cambridge, Massachusetts, and Melbourne, Australia, and also maintains world-wide marketing and sales facilities in North America, Europe, and Asia. The Company's 50,000-sq. ft. R&D facilities and over 120 employees are divided approximately equally between the San Diego and Melbourne locations.
The company broadens its research base by maintaining and supporting collaborative relationships with a large number of academic centers. MitoKor has been awarded over $1 million in federal and state research grants.
| Contact Details: |
| 11494 Sorrento Valley Road |
| San Diego |
| CA |
| 92121 |
| United States of America |
| Tel: | (858) 793 7800 |
| Fax: | (858) 793 7805 |
| Email: | |
| WWW: | www.mitokor.com/
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Recent Publications by MitoKor: |  |
Excitotoxic injury to mitochondria isolated from cultured neurons.
Neuronal death in response to excitotoxic levels of glutamate is dependent... | 24th September, 2005
| MitoKor, San Diego, CA 92121, USA.
| J Biol Chem. 2005 Aug 12;280(32):28894-902. Epub 2005 Jun 2.
DOI Direct Link |
Ectopic expression of the human adenine nucleotide translocase, isoform 3 (ANT-3). Characterization of ligand binding properties.
The adenine nucleotide translocase (ANT) is a key component in maintaining... | 16th September, 2005
| MitoKor,
| Mitochondrion. 2005 Feb;5(1):1-13.
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Co-segregation and heteroplasmy of two coding-region mtDNA mutations within a matrilineal pedigree.
The ENG1 Leber's hereditary optic neuropathy (LHON) family spans six... | 22nd April, 2005
| MitoKor Inc., 12780 High Bluff Drive, Suite 210, San Diego, CA 92130, USA.
| Hum Genet. 2005 Jan;116(1-2):28-32. Epub 2004 Nov 3.
DOI Direct Link |
African Haplogroup L mtDNA sequences show violations of clock-like evolution.
A set of 96 complete mtDNA sequences that belong to the three major... | 5th March, 2005
| MitoKor Inc.,
| Mol Biol Evol. 2004 Oct;21(10):1843-54. Epub 2004 Jun 9.
DOI Direct Link |
Photoreceptor preservation in the S334ter model of retinitis pigmentosa by a novel estradiol analog.
The cytoprotective activity of MITO-4565, a novel, non-hormonal, estradiol... | 26th January, 2005
| MitoKor Inc., 11494 Sorrento Valley Road, San Diego, CA 92121, USA.
| Biochem Pharmacol. 2004 Nov 15;68(10):1971-84.
DOI Direct Link |
→View more MitoKor research publications. |
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