Recent Publications by NeoGenesis: |
Premature ovarian failure and dehydroepiandrosterone.
Since the first successful birth at our centre following treatment with... | 7th March, 2008
| Neogenesis IVF Centre, Athens, Greece.
| Fertil Steril. 2008 Mar 3.
DOI Direct Link |
Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
Screening assays using target-based affinity selection coupled with... | 18th July, 2006
| NeoGenesis Pharmaceuticals, Inc., Cambridge, MA 02139, USA.
| J Biomol Screen. 2006 Mar;11(2):194-207. Epub 2006 Feb 20.
DOI Direct Link |
Comparison of fallopian tube sperm perfusion and intrauterine tuboperitoneal insemination: a prospective randomized study.
OBJECTIVE: To evaluate the results of two different methods of... | 22nd March, 2006
| Neogenesis IVF
| Fertil Steril. 2006 Mar;85(3):735-40.
DOI Direct Link |
Versatile solid-phase synthesis of trisubstituted 1H-pyrido[2,3-d]pyrimidin-4-ones and related heterocycles.
A solid-phase synthesis of trisubstituted 1H-pyrido[2,3-d]pyrimidin-4-ones... | 16th February, 2006
| NeoGenesis Pharmaceuticals, 840 Memorial Drive, Cambridge, Massachusetts
| J Comb Chem. 2005 Jan-Feb;7(1):96-8.
DOI Direct Link |
Interactions of peptide mimics of hyaluronic acid with the receptor for hyaluronan mediated motility (RHAMM).
Using the hyaluronic acid (HA) binding region of the receptor for... | 14th July, 2005
| Department of Physiology and Biophysics, State University of New York,
| J Comput Aided Mol Des. 2004 Oct;18(10):597-614.
|
Aminothiazole inhibitors of HCV RNA polymerase.
Aminothiazole-based inhibitors designed for HCV polymerase display low... | 3rd May, 2005
| NeoGenesis Pharmaceuticals Inc., Department of Chemistry, 840 Memorial
| Bioorg Med Chem Lett. 2005 Jan 3;15(1):115-9.
DOI Direct Link |
A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures.
To realize the full potential of combinatorial chemistry-based drug... | 3rd May, 2005
| NeoGenesis Pharmaceuticals Inc., 840 Memorial Drive, Cambridge, MA 02139,
| J Am Chem Soc. 2004 Dec 1;126(47):15495-503.
DOI Direct Link |
Mapping protein pockets through their potential small-molecule binding volumes: QSCD applied to biological protein structures.
Previously we demonstrated a method, Quantized Surface Complementarity... | 30th December, 2004
| NeoGenesis Pharmaceuticals, Inc., 840 Memorial Dr, Cambridge, MA 02139,
| J Comput Aided Mol Des. 2004 Jan;18(1):55-70.
|
A reagent-based strategy for the design of large combinatorial libraries: a preliminary experimental validation.
Combinatorial library design can be carried out at either the reagent or... | 19th August, 2004
| NeoGenesis Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
| Mol Divers. 2003;7(1):3-14.
|
Combinatorial synthesis of substituted biaryls and heterocyclic arylamines.
In this paper, we report very general conditions that enable... | 11th May, 2004
| NeoGenesis Pharmaceuticals, Inc., 840 Memorial Drive, Cambridge,
| J Comb Chem. 2004 May-Jun;6(3):426-30.
DOI Direct Link |
Recent advances in chemical library synthesis methodology.
The first part of this review highlights recent advances in... | 13th March, 2003
| NeoGenesis Pharmaceuticals Inc, 840 Memorial Drive, Cambridge, MA 02139,
| Curr Opin Drug Discov Devel. 2002 Jul;5(4):580-93.
|
New developments in chemical library synthesis. Norbornenyl tags for use in phase-switching, sequestration, capture-release and soluble support applications.
A new, general chemical library purification platform is reviewed. This... | 13th March, 2003
| NeoGenesis Pharmaceuticals Inc, 840 Memorial Drive, Cambridge, MA 02139,
| Curr Opin Drug Discov Devel. 2002 Jul;5(4):571-9.
|
Chemical genomics: bridging the gap between the proteome and therapeutics.
Technical advances in the areas of DNA sequencing and bioinformatics in... | 13th March, 2003
| NeoGenesis Pharmaceuticals Inc, 840 Memorial Drive, Cambridge, MA 02139,
| Curr Opin Drug Discov Devel. 2002 Jul;5(4):532-9.
|
Chemical genomics: discovery of disease genes and drugs.
[reaction: see text] A solid-phase synthesis of trisubstituted... | 25th February, 2003
| NeoGenesis Pharmaceuticals, 840 Memorial Drive, Cambridge, MA 02139, USA.
| Drug Discov Today. 2002 Mar 1;7(5):292-4.
|