Recent Publications by Amylin Pharmaceuticals Incorporated: |
Exenatide improves hypertension in a rat model of the metabolic syndrome.
BACKGROUND: Exenatide is a peptide incretin mimetic that has... | 17th November, 2009
| Amylin Pharmaceuticals Inc., San Diego, California, USA.
| Metab Syndr Relat Disord. 2009 Aug;7(4):327-34.
DOI Direct Link |
Mechanisms of Amylin/Leptin Synergy in Rodent Models.
The present studies aimed to identify mechanisms contributing to... | 31st October, 2009
| Amylin Pharmaceuticals (V.F.T., J.L.T., G.G., C.W., P.S.G., C.V., D.G.P.,
| Endocrinology. 2009 Oct 29.
DOI Direct Link |
Being supermarket savvy.
The present studies aimed to identify mechanisms contributing to... | 31st October, 2009
| Amylin Pharmaceuticals, Inc., Island Park, NY, USA.
| Diabetes Self Manag. 2009 Sep-Oct;26(5):57, 59-61, 63.
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Improving your diabetes care visits.
The present studies aimed to identify mechanisms contributing to... | 26th September, 2009
| Amylin Pharmaceuticals, Inc., Lexington, Kentucky, USA.
| Diabetes Self Manag. 2009 Jul-Aug;26(4):23-4, 26-8, 31.
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Pharmacology and tolerability of a single dose of exenatide in adolescent patients with type 2 diabetes mellitus being treated with metformin: a randomized, placebo-controlled, single-blind, dose-escalation, crossover study.
OBJECTIVE: This study assessed the pharmacokinetics, pharmacodynamics, and... | 28th July, 2009
| Amylin Pharmaceuticals, Inc., San Diego, California 92121, USA.
| Clin Ther. 2009 Apr;31(4):806-15.
DOI Direct Link |
Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily.
AIMS: To assess treatment satisfaction and weight-related quality of life... | 4th July, 2009
| Amylin Pharmaceuticals Inc., San Diego, CA 92121, USA.
| Diabet Med. 2009 Jul;26(7):722-8.
DOI Direct Link |
Interaction of Leptin and Amylin in the Long-term Maintenance of Weight Loss in Diet-induced Obese Rats.
We have previously shown that combined amylin + leptin agonism elicits... | 23rd June, 2009
| Amylin Pharmaceuticals, Inc., San Diego, California, USA.
| Obesity (Silver Spring). 2009 Jun 18.
DOI Direct Link |
Peptide-lisinopril conjugates: design, synthesis and biological activities.
OBJECTIVE: This study assessed the pharmacokinetics, pharmacodynamics, and... | 6th June, 2009
| Research Chemistry, Amylin Pharmaceuticals Inc., 9360 Towne Centre Drive,
| Adv Exp Med Biol. 2009;611:535-6.
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Synthesis & biological evaluation of PYY(3-36) analogs substituted with alanine.
OBJECTIVE: This study assessed the pharmacokinetics, pharmacodynamics, and... | 6th June, 2009
| Amylin Pharmaceuticals, Inc., 9360 Towne Centre Drive, San Diego, CA
| Adv Exp Med Biol. 2009;611:515-6.
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Implications of amylin receptor agonism: integrated neurohormonal mechanisms and therapeutic applications.
Amylin receptor agonism is emerging as part of an integrated neurohormonal... | 16th April, 2009
| Amylin Pharmaceuticals, Inc, San Diego, CA 92121, USA.
| Arch Neurol. 2009 Mar;66(3):306-10.
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Emerging incretin based therapies for type 2 diabetes: incretin mimetics and DPP-4 inhibitors.
Type 2 diabetes is a chronic disease characterized by impaired insulin... | 14th February, 2009
| Amylin Pharmaceuticals, Inc., 9360 Towne Centre Dr., San Diego, CA 92121,
| Curr Diabetes Rev. 2008 May;4(2):101-9.
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Role of islet-, gut-, and adipocyte-derived hormones in the central control of food intake and body weight: implications for an integrated neurohormonal approach to obesity pharmacotherapy.
Contrary to its historical epithet as a lifestyle disorder, obesity is now... | 14th February, 2009
| Amylin Pharmaceuticals, Inc. 9360 Towne Centre Drive, San Diego, CA 92121,
| Curr Diabetes Rev. 2008 May;4(2):79-91.
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Hormone-based therapies in the regulation of fuel metabolism and body weight.
BACKGROUND: The integrated central actions of hormones secreted from... | 4th February, 2009
| Amylin Pharmaceuticals, Inc., 9360 Towne Centre Drive, San Diego, CA
| Expert Opin Biol Ther. 2008 Nov;8(11):1733-47.
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Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats.
OBJECTIVE: To characterize the interactive effects of amylin with... | 16th January, 2009
| Amylin Pharmaceuticals, Inc, San Diego, CA 92121, USA.
| Int J Obes (Lond). 2008 Aug;32(8):1201-10. Epub 2008 Jun 17.
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Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms.
Previously, we reported that combination treatment with rat amylin (100... | 7th January, 2009
| Amylin Pharmaceuticals, Inc., San Diego, California 92121, USA.
| Endocrinology. 2008 Nov;149(11):5679-87. Epub 2008 Jul 31.
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