Amylin Pharmaceuticals Incorporated

Amylin Pharmaceuticals is a biopharmaceutical company committed to improving lives through the discovery, development and commercialization of innovative medicines. The company was founded in 1987 on the discovery of a hormone, amylin, produced by the same beta cells of the pancreas that make insulin. Since then, Amylin has built a strong foundation on research and development. Amylin's scientists are primarily focused on investigating the potential utility of new peptide hormone candidates. The company has amassed significant research and clinical expertise in metabolic medicine including the areas of diabetes, obesity and cardiovascular disease. By "Challenging Science," Amylin challenges conventional thinking to create innovative approaches to the discovery, development and commercialization of novel therapies for metabolic diseases. Amylin's approach and dedication are rooted in the belief that they will be "Changing Lives" for millions of people - not only with the drugs currently in late-stage development, but also with their pipeline of future therapies.

Contact Details: 9373 Towne Centre Drive San Diego 92121 United States of America Tel: 619 552 2200 Fax: 619 552 2212 Email: WWW: www.amylin.com/

Recent Publications by Amylin Pharmaceuticals Incorporated:
Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms. Previously, we reported that combination treatment with rat amylin (100...	2nd August, 2008	Amylin Pharmaceuticals, Inc. San Diego, CA 92121.	Endocrinology. 2008 Jul 31. DOI Direct Link
Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies. Body weight is regulated by complex neurohormonal interactions between...	25th June, 2008	Amylin Pharmaceuticals, Inc., San Diego, CA 92121, USA.	Proc Natl Acad Sci U S A. 2008 May 20;105(20):7257-62. Epub 2008 May 5. DOI Direct Link
Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats. OBJECTIVE: To characterize the interactive effects of amylin with...	19th June, 2008	Amylin Pharmaceuticals, Inc, San Diego, CA 92121, USA.	Int J Obes (Lond). 2008 Aug;32(8):1201-10. Epub 2008 Jun 17. DOI Direct Link
Combination therapy with amylin and peptide YY[3-36] in obese rodents: anorexigenic synergy and weight loss additivity. Circulating levels of the pancreatic beta-cell peptide hormone amylin and...	18th June, 2008	Amylin Pharmaceuticals Inc., 9360 Towne Centre Drive, San Diego, CA 92121,	Endocrinology. 2007 Dec;148(12):6054-61. Epub 2007 Aug 30. DOI Direct Link
A sulfated, phosphorylated 7 kDa secreted peptide characterized by direct analysis of cell culture media. An unusual sulfotyrosine-, phosphoserine-containing motif was mapped on a...	6th June, 2008	Amylin Pharmaceuticals, Inc., 9360 Towne Centre Drive, San Diego,	J Proteome Res. 2008 Feb;7(2):795-802. Epub 2008 Jan 9. DOI Direct Link
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BioNews Results for Amylin Pharmaceuticals Incorporated:
Icahn Builds On Bio Holdings	Forbes.com:  Aug 14 2008 11:30PM Matching: amylin pharmaceuticals
COURAGE quality-of-life analysis: Slim early gains with PCI soon disappear	Theheart.org:  Aug 14 2008 1:09AM Matching: amylin pharmaceuticals
Biovail Reports Second-Quarter 2008 Financial Results	SmartBrief:  Aug 13 2008 12:39PM Matching: amylin pharmaceuticals
AMYLIN PHARMACEUTICALS INC EPS Estimated At -1.85: Current Recommendation is Sell	Calibre Macro World:  Aug 12 2008 6:54PM Matching: amylin pharmaceuticals
AMYLIN PHARMACEUTICALS INC EPS Estimated At -1.91: Current Recommendation is Neutral	Calibre Macro World:  Aug 11 2008 8:49PM Matching: amylin pharmaceuticals
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Amylin Pharmaceuticals Incorporated Patents:
US Patent No.	Title
5716619	Treatment of type 2 diabetes mellitus
6608029	Methods for regulating gastrointestinal motility
6610824	Amylin agonist peptides and uses therefor
6703359	Inotropic and diuretic effects of exendin and GLP-1
6706689	Treatment of acute coronary syndrome with GLP-1
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