Access Pharmaceuticals

Access Pharmaceuticals is an emerging biotechnology company focused on the development and commercialization of products using the companies targeted delivery systems to improve clinical outcomes for patients. Together with our subsidiaries we have proprietary patents or rights to a number of drug delivery platforms,Synthetic polymer targeted delivery,Vitamin mediated targeted delivery, Vitamin mediated oral delivery, Bioerodible cross-linker technology, and Hydrogel particle aggregate chnology. The company’s primary development focus is in the area of oncology with its polymer therapeutics program. The company’s lead product, AP5346, is in Phase II clinical development and is a polymer of DACH-platinum, the active principal of oxaliplatin (Eloxatin; sanofiventis).

Contact Details: 2600 N. Stemmons Freeway Suite 176 Dallas 75207-2107 United States of America Tel: 214 905 5100 Fax: 214 905 5101 Email: akc@accesspharma.com WWW: www.accesspharma.com/

Recent Publications by Access Pharmaceuticals:
Synthesis and characterization of AP5346, a novel polymer-linked diaminocyclohexyl platinum chemotherapeutic agent. Syntheses of the novel polymer-bound platinum-based chemotherapeutic agent...	16th May, 2007	Access Pharmaceuticals, Inc., 2600 Stemmons Freeway, Suite 176, Dallas,	Bioconjug Chem. 2006 Sep-Oct;17(5):1270-9. DOI Direct Link
Preclinical efficacy and pharmacokinetics of AP5346, a novel diaminocyclohexane-platinum tumor-targeting drug delivery system. PURPOSE: AP5346 is designed to target a diaminocyclohexane platinum (Pt)...	19th July, 2006	Access Pharmaceuticals, Inc., Dallas, Texas, USA.	Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2248-54. DOI Direct Link
Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. Targeted chemotherapy for cancer treatment offers a great potential...	22nd December, 2004	Access Pharmaceuticals Australia Pty Ltd., Targeted Delivery, Unit 5,	J Inorg Biochem. 2004 Oct;98(10):1625-33. DOI Direct Link
Use of targeting agents to increase uptake and localization of drugs to the intestinal epithelium. Despite early successes in oral drug delivery of small molecules such as...	16th December, 2004	Access Pharmaceuticals Australia Pty Ltd, Unit 5 Gibbes St. 2067 NSW	J Drug Target. 2004 Feb;12(2):113-23. DOI Direct Link

BioNews Results for Access Pharmaceuticals:
Amylin Pharmaceuticals to Present at Thomas Weisel Healthcare, BioCentury NewsMakers, and Morgan Stanley Globa	SmartBrief:  Sep 1 2008 12:22AM Matching: access pharmaceuticals
Amylin Pharmaceuticals to Present at Thomas Weisel Healthcare, BioCentury NewsMakers, and Morgan Stanley Globa	Montana's News Station:  Aug 31 2008 2:04PM Matching: access pharmaceuticals
Amylin Pharmaceuticals to Present at Thomas Weisel Healthcare, BioCentury NewsMakers, and Morgan Stanley Globa	KSLA:  Aug 30 2008 3:44PM Matching: access pharmaceuticals
Amylin Pharmaceuticals to Present at Thomas Weisel Healthcare, BioCentury NewsMakers, and Morgan Stanley Globa	KRON4:  Aug 30 2008 11:17AM Matching: access pharmaceuticals
Is Bigger Really Better?	Signals Magazine:  Aug 29 2008 3:44AM Matching: access pharmaceuticals
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Access Pharmaceuticals Patents:
US Patent No.	Title
7166733	O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes
5336762	Polychelating agents for image and spectral enhancement (and spectral shift)
5672334	Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
5707604	Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
5753261	Lipid-coated condensed-phase microparticle composition
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