Recent Publications by Orphan Medical Incorporated: |
The clinical development of gamma-hydroxybutyrate (GHB).
The discovery of gamma-hydroxybutyrate (GHB) over 40 years ago led to its... | 3rd September, 2008
| Orphan Medical, Inc., A subsidiary of Jazz Pharmaceuticals, Inc., Palo
| Curr Drug Saf. 2006 Jan;1(1):99-106.
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Further evidence supporting the use of sodium oxybate for the treatment of cataplexy: a double-blind, placebo-controlled study in 228 patients.
BACKGROUND AND PURPOSE: To measure the effect of the nocturnal... | 8th February, 2006
| Orphan Medical, Inc., 13911 Ridgedale Drive Suite 250, Minnetonka, MN
| Sleep Med. 2005 Sep;6(5):415-21.
DOI Direct Link |
Pharmacotherapy for cataplexy.
A variety of medications representing several major drug classes improve... | 29th January, 2005
| Orphan Medical, Inc., Medical Affairs, 13911 Ridgedale Drive, Suite 250,
| Sleep Med Rev. 2004 Oct;8(5):355-66.
DOI Direct Link |
The Xyrem risk management program.
Sodium oxybate, also known as gamma-hydroxybutyric acid (GHB), was... | 13th August, 2004
| Orphan Medical Inc., Minnetonka, Minnesota 55305, USA.
| Drug Saf. 2004;27(5):293-306.
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The pharmacokinetics of sodium oxybate oral solution following acute and chronic administration to narcoleptic patients.
This trial was conducted to evaluate the pharmacokinetics and safety of a... | 15th June, 2004
| Orphan Medical, Inc., 13911 Ridgedale Drive, Suite 250, Minnetonka, MN
| J Clin Pharmacol. 2004 Mar;44(3):253-7.
DOI Direct Link |
From club drug to orphan drug: sodium oxybate (Xyrem) for the treatment of cataplexy.
Narcolepsy, a rare disease with a prevalence of 0.05% in the general... | 11th February, 2004
| Orphan Medical, Inc., Minnetonka, Minnesota 55305, USA.
| Pharmacotherapy. 2003 Sep;23(9):1205-9.
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The influence of gender and food on the pharmacokinetics of sodium oxybate oral solution in healthy subjects.
Sodium oxybate (Xyrem; gamma-hydroxybutyrate) oral solution was recently... | 15th March, 2003
| Orphan Medical, Inc., 13911 Ridgedale Drive, Suite 250, Minnetonka, MN
| J Clin Pharmacol. 2003 Jan;43(1):59-65.
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Sodium oxybate (GHB) for treatment of cataplexy.
Sodium oxybate (Xyrem; gamma-hydroxybutyrate) oral solution was recently... | 12th December, 2002
| Orphan Medical, Inc., Minnetonka, Minnesota 55305, USA.
| Pharmacotherapy. 2002 Jun;22(6):798-9; discussion 799.
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