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ProthericsWe are a biopharmaceutical business, with approximately 125 employees and operations in the United Kingdom, United States and Australia. We are focused on immunotherapeutic research and development, and were formed in September 1999 through the merger of Proteus International Plc and Therapeutic Antibodies Inc.
Our products are based on two proprietary technology platforms:
Highly purified polyclonal antibodies for acute medical emergency applications. These products are in late stage development or already on the market and include CroFab™, DigiFab™ and CytoTAb® .
Novel peptide-conjugate vaccines to treat chronic diseases. These products are in pre-clinical or clinical development and include GnRH(gonadotropin releasing hormone) and angiotensin vaccines.
| Contact Details: |
| The Health Business and Technical Park |
| Runcorn |
| Cheshire |
| W47 4QF |
| United Kingdom |
| Tel: | 01928 518 000 |
| Fax: | 01928 518 002 |
| Email: | barry.riley@protherics.com |
| WWW: | www.protherics.co.uk/
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Recent Publications by Protherics: |  |
Pharmacokinetics of glucarpidase in subjects with normal and impaired renal function.
Glucarpidase (formerly known as carboxypeptidase G2 or CPG2) is being... | 20th May, 2008
| Protherics PLC, The Heath Business & Technical Park, Runcorn, Cheshire,
| J Clin Pharmacol. 2008 Mar;48(3):279-84. Epub 2008 Jan 11.
DOI Direct Link |
Optimal conditions for the papain digestion of polyclonal ovine IgG for the production of bio-therapeutic Fab fragments.
In the present paper, we describe a rapid method for the determination of... | 8th March, 2008
| Process Development Group, Protherics U.K. Ltd, Blaenwaun, Ffostrasol,
| Biotechnol Appl Biochem. 2005 Oct;42(Pt 2):163-8.
DOI Direct Link |
Antibody production: polyclonal-derived biotherapeutics.
Antibody based therapies using monoclonal or polyclonal antibodies are... | 22nd May, 2007
| Process Development Group, Protherics UK Ltd, Blaenwaun, Ffostrasol,
| J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Mar 15;848(1):2-7.
DOI Direct Link |
Optimised affinity purification of polyclonal antibodies from hyper immunised ovine serum using a synthetic Protein A adsorbent, MAbsorbent A2P.
This report describes the applicability of a synthetic chromatography... | 19th May, 2005
| Process Development Group, Protherics Ltd., Blaenwaun, Ffostrasol,
| J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jan 25;814(2):209-15.
DOI Direct Link |
Evaluation of two carrier protein-angiotensin I conjugate vaccines to assess their future potential to control high blood pressure (hypertension) in man.
AIMS: We aim to modulate the renin-angiotensin system (RAS) by active... | 3rd February, 2004
| Protherics plc. (PMD), The Heath Business & Technical Park, Runcorn, UK.
| Br J Clin Pharmacol. 2003 Nov;56(5):505-12.
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