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Protiva Biotherapeutics

Drug development using non-viral lipid-mediated gene delivery.


Contact Details:
150 - 8900 Glenlyon Parkway
Burnaby
British Columbia
V5J 5J8
Canada
Tel:
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Email:
WWW:

www.protivabio.com/




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Recent Publications by Protiva Biotherapeutics:

Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes.
The systemic application of nucleic acid drugs requires delivery systems...
24th January, 2009
Protiva Biotherapeutics, Burnaby, BC, Canada. Mol Ther. 2006 Feb;13(2):328-37. Epub 2005 Nov 7.
DOI Direct Link
Overcoming the innate immune response to small interfering RNA.
Many types of nucleic acid, including canonical small interfering RNA...
18th September, 2008
Protiva Biotherapeutics, Burnaby, British Columbia, Canada V5G 4Y1. Hum Gene Ther. 2008 Feb;19(2):111-24.
DOI Direct Link
2'-O-methyl-modified RNAs act as TLR7 antagonists.
RNA molecules such as single-stranded RNA (ssRNA) and small interfering...
27th February, 2008
Protiva Biotherapeutics, Burnaby, British Columbia, Canada. Mol Ther. 2007 Sep;15(9):1663-9. Epub 2007 Jun 19.
DOI Direct Link
Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo.
Targeted silencing of disease-associated genes by synthetic short...
1st August, 2007
Protiva Biotherapeutics, 100-3480 Gilmore Way, Burnaby, BC, Canada V5G Mol Ther. 2006 Mar;13(3):494-505. Epub 2005 Dec 15.
DOI Direct Link
Lipid encapsulation enables the effective systemic delivery of polyplex plasmid DNA.
Using a new controlled mixing process, highly transfection-competent...
23rd May, 2007
Protiva Biotherapeutics, Burnaby, British Columbia, Canada. Mol Ther. 2007 Apr;15(4):713-20. Epub 2007 Feb 13.
DOI Direct Link

View more Protiva Biotherapeutics research publications.

Press Releases on Protiva Biotherapeutics:

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Previous Claims of siRNA Therapeutic Effects Called into Question by Report in 'Human Gene Therapy' 2nd September, 2008 Mary Ann Liebert, Inc.
NEW ROCHELLE, N.Y., Sept. 2 /PRNewswire/ -- The many recent reports documenting the therapeutic efficacy of short interfering RNAs (siRNAs) in animal models of human disease may actually be

BioNews Results for Protiva Biotherapeutics:

Talecris to Invest $268.7 Million to Expand its Manufacturing Facility in Clayton
Genetic Engineering News:  Nov 15 2009 8:17AM Matching: biotherapeutics
Drug firm expanding NC operation, adding 260 jobs
WCNC:  Nov 15 2009 2:58AM Matching: biotherapeutics
Rockland job losses could hit 600 by 2011
Lower Hudson Online:  Nov 14 2009 10:50PM Matching: biotherapeutics
Talecris to Invest $268.7 Million to Expand its Manufacturing Facility in Clayton
Pharma Live:  Nov 14 2009 10:40PM Matching: biotherapeutics
Drug firm expanding N.C. operations, adding 260 jobs
Fayetteville Online:  Nov 14 2009 5:13PM Matching: biotherapeutics
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View more Protiva Biotherapeutics news.

Protiva Biotherapeutics Patents:

US Patent No.Title
6841537 Combination therapy using nucleic acids and conventional drugs
6410328 Sensitizing cells to compounds using lipid-mediated gene and compound delivery

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