Senomyx

Our Business

We seek to be the leader in discovering new and improved proprietary flavor and fragrance molecules for use in a wide range of consumer products. Our integrated technology platform combines an enhanced understanding of the biology of taste and smell with many of the same technologies and advancements that pharmaceutical companies have recently begun using to more efficiently discover new medicines. We have entered into a product discovery and development collaboration with Kraft Foods, Inc., the largest branded food company in the U.S. We have also entered into technology collaborations with Aurora Biosciences Corporation and Incyte Genomics, Inc. in order to enhance our technology platform and gain access to additional intellectual property.





Our Technologies



We are designing and assembling a proprietary technology platform to enhance and industrialize the discovery process and overcome many of the limitations of traditional discovery programs for new flavor and fragrance molecules. Our team of world-class scientists and industry experts is incorporating recent advancements in receptor biology, combinatorial chemistry, high-throughput screening and bioinformatics into an integrated technology platform designed to enable the rapid, efficient discovery of new and improved proprietary molecules. Examples of potential product molecules include those that block the bitter taste of coffee, molecules that increase the salty taste of low sodium snacks and molecules that block unpleasant odors.

Contact Details: 11099 North Torrey Pines Drive La Jolla CA 92037 United States of America Tel: (858) 646-8300 Fax: (858) 404-0752 Email: sherry.dollins@senomyx.com WWW: www.senomyx.com/

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Recent Publications by Senomyx:
New insights on the role of CXCR4 in cancer metastasis. The evolutionarily conserved chemokine superfamily encodes small peptide...	14th August, 2008	Department of Biology, Senomyx, Inc, 4767 Nexus Center Drive, San Diego,	J Pathol. 2008 Jul;215(3):211-3. DOI Direct Link
Small molecule activator of the human epithelial sodium channel. The epithelial sodium channel (ENaC), a heterotrimeric complex composed of...	20th June, 2008	Senomyx, Inc., San Diego, California 92121, USA.	J Biol Chem. 2008 May 2;283(18):11981-94. Epub 2008 Mar 6. DOI Direct Link
Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Variation in human taste is a well-known phenomenon. However, little is...	7th December, 2007	Senomyx, 4767 Nexus Centre Drive, San Diego, California 92121, USA.	Curr Biol. 2007 Aug 21;17(16):1403-8. DOI Direct Link
Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression. BACKGROUND: Research on olfactory G-protein coupled receptors (GPCRs) has...	9th June, 2005	Senomyx, Inc, 11099 North Torrey Pines Road, La Jolla, CA 92037, USA.	BMC Cell Biol. 2004 Sep 15;5:34. DOI Direct Link
Receptors for bitter, sweet and umami taste couple to inhibitory G protein signaling pathways. Taste receptors are thought to couple to the G protein Galpha-gustducin to...	20th April, 2005	Senomyx, Inc., 11099 North Torrey Pines Road, La Jolla, CA 92037, USA.	Eur J Pharmacol. 2004 Apr 12;489(3):139-49. DOI Direct Link
→View more Senomyx research publications.

BioNews Results for Senomyx:
Senomyx, Solae Reach Milestone in Effort to Improve Taste of Soy Protein; Innovative 'Bitter Blocker' Technolo	Freshnews.com:  Sep 18 2008 1:41AM Matching: senomyx
Human T2R61 taste receptor and related assays for identifying human bitter taste modulators	PharmCast:  Jul 31 2008 3:42AM Matching: senomyx

Senomyx Patents:
US Patent No.	Title
7419791	Methods of screening compounds using a T1R3 hetero-oligomeric taste receptor
7294474	Functional assays for identifying compounds that modulate T1R2/T1R3 (sweet) taste
7291485	G.alpha..sub.q protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
7244835	T1R taste receptors and genes encoding same
7241880	T1R taste receptors and genes encoding same
→View more Senomyx patents.

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