Ariad Pharmaceuticals Incorporated

ARIAD Pharmaceuticals, Inc. is focused on the discovery and development of novel and proprietary drugs based on its understanding of the inner-workings of cells and the genes involved in disease. The Company has developed a product based on its gene regulation technology to treat graft-versus-host disease, a complication of bone marrow transplantation involving an attack by a patient's immune system on healthy tissue. This product entered Phase 1 human clinical trials in December 1998. All of the Company's other drug candidates are in the pre-clinical stage as at the end of 1998.

Contact Details: 26 Landsdowne Street Cambridge MA 02139-4234 United States of America Tel: 617 494 0400 Fax: 617 494 8144 Email: investor@ariad.com WWW: www.ariad.com/

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Recent Publications by Ariad Pharmaceuticals Incorporated:
Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors. Novel N(9)-arenethenyl purines, optimized potent dual Src/Abl tyrosine...	12th August, 2008	ARIAD Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, MA 02139,	Bioorg Med Chem Lett. 2008 Sep 1;18(17):4907-12. Epub 2008 Jun 18. DOI Direct Link
SAR of carbon-linked, 2-substituted purines: synthesis and characterization of AP23451 as a novel bone-targeted inhibitor of Src tyrosine kinase with in vivo anti-resorptive activity. Targeted disruption of the pp60(src) (Src) gene has implicated this...	9th April, 2008	ARIAD Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, MA 02139,	Chem Biol Drug Des. 2008 Feb;71(2):97-105. Epub 2008 Jan 3. DOI Direct Link
Determination of protein-DNA sequence specificity by PCR-assisted binding-site selection. Binding-site selection is used to determine the target specificity of a...	22nd February, 2008	Ariad Pharmaceuticals, Inc., Cambridge, Massachusetts, USA.	Curr Protoc Mol Biol. 2001 May;Chapter 12:Unit 12.11. DOI Direct Link
Crystal structure of the T315I mutant of AbI kinase. Imatinib (Gleevec) is currently the frontline therapy for chronic myeloid...	20th October, 2007	ARIAD Pharmaceuticals Inc, 26 Landsdowne St., Cambridge, MA 02139, USA.	Chem Biol Drug Des. 2007 Sep;70(3):171-81. DOI Direct Link
Chemical biology and drug design: three-dimensional, dynamic, and mechanistic nature of two multidisciplinary fields. Protein phosphorylation has been exploited by Nature in profound ways to...	10th March, 2007	Chemical Biology & Drug Design, Drug Discovery, ARIAD Pharmaceuticals,	Chem Biol Drug Des. 2006 Mar;67(3):196-200. DOI Direct Link
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BioNews Results for Ariad Pharmaceuticals Incorporated:
Lehman Bros Changes EPS Estimate of ARIAD PHARMACEUTICALS INC: Current Recommendation is Overweight	Calibre Macro World:  Sep 30 2008 6:52PM Matching: ariad pharmaceuticals
Lehman Bros Changes EPS Estimate of ARIAD PHARMACEUTICALS INC: Current Recommendation is Overweight	Macro World Investor:  Sep 30 2008 6:48PM Matching: ariad pharmaceuticals
Ariad's Patent: A Court Rules	Corante:  Sep 26 2008 10:56AM Matching: ariad pharmaceuticals
Ariad disappointed at patent ruling	IP World Online:  Sep 26 2008 6:06AM Matching: ariad pharmaceuticals
Court Ruling Raises Concerns About Ariad's Conduct and Patents	Seeking Alpha:  Sep 25 2008 10:30AM Matching: ariad pharmaceuticals
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Ariad Pharmaceuticals Incorporated Patents:
US Patent No.	Title
7238679	Heterocycles and uses thereof
6303319	Cell based assay for identifying sh2-domain-specific signal transducer antagonist
6258823	Materials and method for treating or preventing pathogenic fungal infection
6251620	Three dimensional structure of a ZAP tyrosine protein kinase fragment and modeling methods
6207397	In vitro fluorescence polarization assay
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