Recent Publications by The Scripps Research Institute: |
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
Only one broadly neutralizing anti-HIV antibody, 2G12, recognises the... | 4th October, 2008
| aGlycobiology Institute, Department of Biochemistry, University of Oxford,
| AIDS. 2008 Oct 18;22(16):2214-2217.
DOI Direct Link |
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist.
The adenosine class of heterotrimeric guanine nucleotide-binding protein... | 4th October, 2008
| Department of Molecular Biology, The Scripps Research Institute, La Jolla,
| Science. 2008 Oct 2.
DOI Direct Link |
Antisense masking reveals contributions of mRNA-rRNA base pairing to translation of Gtx and FGF2 mRNAs.
We previously showed that a 9-nucleotide sequence from the 5' leader of... | 4th October, 2008
| Neurobiology, The Scripps Research Institute, La Jolla, CA 92037.
| J Biol Chem. 2008 Oct 2.
DOI Direct Link |
Chemical addressability of ultraviolet-inactivated viral nanoparticles (VNPs).
BACKGROUND: Cowpea Mosaic Virus (CPMV) is increasingly being used as a... | 3rd October, 2008
| Department of Cell Biology, and Center for Integrative Molecular
| PLoS ONE. 2008 Oct 2;3(10):e3315.
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The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.
Transcriptional dysregulation has emerged as a core pathologic feature of... | 3rd October, 2008
| Department of Molecular Biology, The Scripps Research Institute, La Jolla,
| Proc Natl Acad Sci U S A. 2008 Sep 30.
DOI Direct Link |
Differential Effects of Acute Alcohol on Prepulse Inhibition and Event-Related Potentials in Adolescent and Adult Wistar Rats.
Background: Previous studies have demonstrated that adolescent and adult... | 3rd October, 2008
| From The Scripps Research Institute, Department of Molecular and
| Alcohol Clin Exp Res. 2008 Sep 25.
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Severe iron overload with a novel aminolevulinate synthase mutation and hepatitis C infection. A case report.
A 55 year old man with a history of chronic hepatitis C infection was... | 1st October, 2008
| Department of Molecular and Experimental Medicine, The Scripps Research
| Blood Cells Mol Dis. 2008 Sep 25.
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A Copper(I)-Catalyzed 1,2,3-Triazole Azide-Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant.
Treatment with HIV-1 protease inhibitors, a component of highly active... | 1st October, 2008
| Departments of Molecular and Experimental Medicine, Molecular Biology, and
| J Med Chem. 2008 Sep 30.
DOI Direct Link |
Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity.
The V3 loop of HIV-1 gp120 is considered occluded on many primary viruses.... | 30th September, 2008
| The Scripps Research Institute, Department of Immunology and Microbial
| Virology. 2008 Sep 24.
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Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia.
Friedreich ataxia (FRDA) is caused by hyperexpansion of GAA*TTC repeats... | 30th September, 2008
| Center for Genome Research, Institute of Biosciences and Technology, Texas
| Nucleic Acids Res. 2008 Sep 27.
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Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands.
Cannabinoid compounds affect synaptic activity and plasticity in numerous... | 26th September, 2008
| Molecular and Integrative Neurosciences Department, The Scripps Research
| J Neurosci Res. 2008 Sep 24.
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A Genetically Encoded Boronate-Containing Amino Acid.
Cannabinoid compounds affect synaptic activity and plasticity in numerous... | 26th September, 2008
| Department of Chemistry and The Skaggs Institute for Chemical Biology, The
| Angew Chem Int Ed Engl. 2008 Sep 24.
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Species specificity in major urinary proteins by parallel evolution.
Species-specific chemosignals, pheromones, regulate social behaviors such... | 26th September, 2008
| Department of Cell Biology, The Scripps Research Institute, La Jolla,
| PLoS ONE. 2008 Sep 25;3(9):e3280.
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Evolution of CCR5 Use Before and During Coreceptor Switching.
The envelope (env) gene of HIV-1 undergoes rapid divergence from the... | 26th September, 2008
| Department of Immunology, The Scripps Research Institute, La Jolla, CA
| J Virol. 2008 Sep 24.
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Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels.
TRPA1 is a member of the transient receptor potential (TRP) family of ion... | 26th September, 2008
| Department of Cell Biology, The Scripps Research Institute, La Jolla,
| J Neurosci. 2008 Sep 24;28(39):9640-51.
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