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SLIL BiomedicalSLIL Biomedical Corp. is an early-stage drug discovery company, focused on developing new treatments for cancer and other diseases. SLIL has patented technology and a pipeline of potential drugs, the first of which is expected to enter a human clinical trial for cancer in early 2002.
SLIL has a strong board and well-qualified management. The Company also has outstanding scientific resources, led by Dr. Laurence Marton and Dr. Benjamin Frydman. Dr. Marton is considered a leading expert in the field of polyamines and their role in cell function and human disease, while Dr. Frydman is a world-renowned organic chemist and a leader in the field of porphyrin research.
| Contact Details: |
| 37 Kessel Court, Suite 211 |
| Madison |
| Wisconsin |
| 53711-6233 |
| United States of America |
| Tel: | 608-270-3712 |
| Fax: | 608-270-3715 |
| Email: | mkjohnson@slil.com |
| WWW: | www.slil.com/
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Recent Publications by SLIL Biomedical: |  |
Long-chain polyamines (oligoamines) exhibit strong cytotoxicities against human prostate cancer cells.
alpha N,(omega)N-bis(ethyl) octamine SL-11160, decamine SL-11159,... | 13th November, 2004
| SLIL Biomedical Corp., 535 Science Drive, Suite C, Madison, WI 53711, USA.
| Bioorg Med Chem. 2003 Sep 1;11(18):4121-31.
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Macrocyclic polyamines deplete cellular ATP levels and inhibit cell growth in human prostate cancer cells.
In solid tumors, when O(2) partial pressure drops below 10 mmHg, ATP... | 6th April, 2004
| SLIL Biomedical Corp., 535 Science Dr., Suite C, Madison, Wisconsin
| J Med Chem. 2004 Feb 12;47(4):1051-9.
DOI Direct Link |
Cyclopropane-containing polyamine analogues are efficient growth inhibitors of a human prostate tumor xenograft in nude mice.
Polyamine analogues 7, 10, 18, 27, and 32 containing cyclopropane rings... | 13th November, 2003
| SLIL Biomedical Corporation, 535 Science Drive, Suite C, Madison, WI
| J Med Chem. 2003 Oct 9;46(21):4586-600.
DOI Direct Link |
HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression.
HIV integration within host cell genomic DNA is a requisite step of the... | 2nd August, 2003
| SLIL Biomedical Corporation, Menlo Park, California, USA.
| J Acquir Immune Defic Syndr. 2003 Jul 1;33(3):308-20.
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A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice.
PURPOSE: We tested the polyamine analog SL-11093... | 30th July, 2003
| SLIL Biomedical Corporation, Suite C, 535 Science Dr, Madison, WI
| Cancer Chemother Pharmacol. 2003 Jun;51(6):488-92. Epub 2003 Apr 15.
DOI Direct Link |
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