BAC
adds IgM and IgA matrices to its CaptureSelect Toolbox for antibody
purification - new products address significant gaps in the antibody
purification market
Naarden, The Netherlands, 21st April 208 – BAC BV, the Bio Affinity
Company, today announced the addition of two new products to its CaptureSelect®
Antibody Toolbox. The new products, affinity matrices for the purification of
IgA and IgM, address a substantial need in the antibody purification market,
which up until now has had no satisfactory purification media for these
antibody types. Both IgA and IgM are regarded as important potential
therapeutics and the CaptureSelect IgA and IgM affinity products will make
research and development in this area simpler, more efficient and more viable.
The new products are available for purchase through the Company’s product
website, www.captureselect.com .
The CaptureSelect IgA and IgM products offer unparalleled specificity and
product purity in a one-step purification process. CaptureSelect Human IgA
affinity matrix contains an affinity ligand that binds to a unique domain that
is present on all subclasses of human IgA, with no cross reactivity with IgM
or IgG. The CaptureSelect IgM affinity matrix contains an affinity ligand that
is directed towards a unique domain that is present on both human and mouse
IgM antibodies, and offers no cross-reactivity with human or mouse IgA or IgM.
“The products in our CaptureSelect Antibody Toolbox range simplify and
streamline the purification of antibodies in the lab,” explained Mark ten
Haaft, Director of Ligand Application at BAC. “We have developed standardized
protocols that enable researchers to follow a simple one-step process with no
need for method testing or lengthy optimization steps. Additionally, the
unique specificity of the products provides researchers with total confidence
that the affinity matrix they choose will be a perfect match for their
target”.
Laurens Sierkstra, CEO of BAC, commented: “We are very pleased to add these
products to our off-the-shelf range and address such an important market need.
The CaptureSelect Antibody Toolbox allows us to make the technology that we
have already proven at industrial scale, accessible at an R&D scale for bench
research.”
The CaptureSelect Antibody Toolbox contains the following additional products:
-
CaptureSelect Fab kappa affinity matrix: for all human antibodies containing
kappa light chains
-
CaptureSelect Fab lambda affinity matrix: for all human antibodies
containing lambda light chains
-
CaptureSelect Human Fc affinity matrix: for all subclasses of human IgG
-
CaptureSelect Multi Species affinity matrix: for IgG from multiple species
BAC’s
CaptureSelect ligands have been used for a wide variety of purification needs,
from monoclonal antibody and virus purification to plasma protein depletion.
The Antibody Toolbox products can solve virtually any purification challenge
for a range of antibody formats including Fc fusion proteins, antibody
fragments, and all antibody classes. The products in the Antibody Toolbox are
produced using BAC’s proprietary affinity ligand technology, based on the
unique single chain antibodies found in Camelids, and manufactured using a
completely animal component-free S.cerevisiae system.
-Ends-
About BAC
BAC BV – the Bio Affinity Company – offers a wide range of products and
services for affinity purification of biological materials from complex media.
The Company’s proprietary CaptureSelect® affinity ligands, based on Camelid
single chain antibody fragments, have been proven to be suitable in a wide
range of biological applications including Life Science Research and
Biomanufacturing.
CaptureSelect® ligand technology is based on selection of single chain
antibody fragments with desirable chromatographic characteristics including
robustness, high specificity and flexibility. Suitable ligands are cloned and
expressed in high-titers through an animal-free Saccharomyces cerevisiae-based
process.
BAC BV was established in 1995 as a Unilever subsidiary. Currently the Company
employs 28 people with an R&D laboratory facility and a state-of-the-art ISO
9001 certified manufacturing plant located in The Netherlands. For more
information about BAC, visit our website at www.bac.nl. For more information
about CaptureSelect® products, visit our website at
www.captureselect.com
Media enquiries:
Kathryn Robertson, College Hill
Kathryn.Robertson@collegehill.com
Tel: +44 (0)1260 296 506
