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Eden Biodesign and Aquapharm BioDiscovery join forces to help combat MRSA

September 2006 Eden Biodesign (Liverpool, UK), a leading provider of development and manufacturing services for new medicines, announced today that it has been selected by Aquapharm BioDiscovery (Oban, UK), a leading marine biotechnology company, to develop AQP001, a novel protein drug candidate.

AQP001 is a natural marine product identified by Aquapharm BioDiscovery scientists as a broad spectrum antibacterial agent active against bacteria resistant to standard antibiotics, including MRSA.

Eden Biodesign will use its extensive expertise in protein drug development and manufacturing to assist Aquapharm BioDiscovery in large scale standardised production of AQP001 required for further testing and clinical development of this new therapeutic.

Dr Crawford Brown, CEO of Eden Biodesign commented: “To our knowledge, this is the first instance of a protein pharmaceutical derived from a marine organism entering commercial development and we are delighted to utilise our expertise and experience in support of Aquapharm BioDiscovery.”

Dr Andrew Mearns Spragg, CEO of Aquapharm BioDiscovery said: “This deal represents a major step forward in the commercialisation of natural products from marine organisms. Aquapharm BioDiscovery research already identified new compounds with pharmaceutical and industrial potential from marine organisms and the company is well positioned to commercially exploit this valuable natural resource.”

Aquapharm Biodiscovery has been awarded a grant from the National Biomanufacturing Centre

(NBC) Access Fund administered by the Northwest Regional Development Agency (NWDA) towards the cost of the project. The project will be executed at the state of the art National Biomanufacturing Centre (NBC), a £34.25 million initiative developed and owned by the NWDA, which is being officially opened later this year.

Dr Linda Magee, NWDA Biotechnology Sector Director & Head of Bionow, commented: “We are delighted that the National Biomanufacturing Centre is able to provide practical help to the UK biotech industry in commercialisation of their discoveries and wish Aquapharm every success with the development of this exciting project.”

Eden Biodesign is the operator of the NBC on behalf of NWDA.

Ends

For further details contact: Charmaine Colvin on 0870 240 5536 or e-mail charmaine@redheadpr.co.uk 


Notes to editors

The National Biomanufacturing Centre


The £34.25 million National Biomanufacturing Centre is a Government-funded initiative led by the Northwest Regional Development Agency (NWDA) additionally funded through the European Regional Development Fund and the Department of Trade and Industry and aims to establish England’s Northwest as one of the foremost biomanufacturing centres in Europe and will be officially opened in November 2006.

The centre provides the expertise and facilities to support new and existing biotechnology companies, offering product development services designed to fill in the skill and resource gaps that exist within these organisations. It also provides training in biomanufacturing and analytical sciences, delivering the skilled workforce required to expand the UK biopharmaceutical sector.

There is also an Access Fund of nearly £3 million funded by the Department of Trade and Industry and the European Regional Development Fund which is available to qualifying small-to-medium companies and research groups in the biotechnology sector to assist them in purchasing development and clinical manufacturing services from the Centre.

Eden Biodesign

Eden Biodesign is a successful international biopharmaceutical development and manufacturing services business that provides ‘state of the art’ development and manufacturing services to biotech clients across Europe, the USA and Asia. It promises all clients a committed service plus the knowledge and expertise to guide clients through process development, manufacturing, regulatory and technology transfer challenges.

The company uses the principles of ‘Good Science’ at every step of biopharmaceutical development to design programmes and processes that deliver clinically and commercially valuable products, with an accomplished and attentive level of project management that clients need.

Although the NBC will be officially opening on 1 November 2006, Eden Biodesign has been operating at the NBC since the beginning of this year, working with clients including SR Pharma, Onyvax and Liverpool University.

Aquapharm BioDiscovery

Aquapharm BioDiscovery is the UK’s premier marine biotechnology company discovering new compounds and novel production systems from the microbes of the marine environment. The company was founded in 2000 in Scotland by Dr Andrew Mearns Spragg and Dr Kathryn Fraser, both PhD graduates of Heriot-Watt University of Edinburgh.

Aquapharm BioDiscovery has a substantial collection of unique marine bacteria and fungi obtained from samples collected from diverse and extreme marine habitats, including the arctic and the deep sea. Aquapharm BioDiscovery uses its patented technology for manipulation of marine microbial communities to stimulate the development and production of new molecules for pharmaceutical, nutraceutical and industrial applications. To date, Aquapharm BioDiscovery has identified novel antibiotic and anti-fungal agents, new high yield carotenoid pigments sources, new enzymes and other functional molecules. In addition to its own research activities, Aquapharm collaborates with external companies including Dowpharma to search Aquapharm’s proprietary libraries for compounds of interest to partner company’s R&D programs.

 

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