MedicWave launches Proteinmarker Detection SoftwareTM (PDSTM) 2.0, the state of the art software for proteomic data analysis

March 2007.  MedicWave launches the software, Proteinmarker Detection Software™ 2.0, an analysis tool specialized in high dimensional proteomic data analysis, especially peak extraction, fast multi-spectra segregation, and multiple protein-pattern detection.

This next generation data analysis software, adds significant additional capability in terms of unique peak extraction algorithms and effective data mining methods for rapid comparison between different biomarker groups.

The software detects and identifies relevant protein-markers and patterns in high dimensional proteomic data using a numerous set of extensive cross-validation procedures, built on many measurements with true statistical differences between the groups.

The PDSTM is entirely automatic and requires minimal supervision. Extensive cross-validation procedures are performed to prevent data from over-fitting. The validation-set is also carefully kept outside the training procedure throughout the whole process. Results are therefore unaffected by human interaction and kept as unbiased as possible.

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NOTES TO EDITORS: About proteomic data analysis

The central importance of proteomics lies in the fact that proteins are the molecules that carry out virtually all biological processes. To understand any biological phenomenon, the role proteins play must therefore be understood. Not only are proteins axiomatic to the life of
the healthy cell, but they are central to disease and its treatment too. Nearly all drug targets are proteins, and most drugs work by correcting the protein abnormalities that cause disease.

The analysis and interpretation of the volumes of proteomic data often remains a bioinformatics challenge, despite the advances in proteomic data analysis and data mining technology today. It is a burdensome data analysis process that takes time and there is often a need to inspect individual protein spectra visually and laboriously in order to verify that spectral peaks identified are real.

Advances in information technology bring powerful computational capabilities to laboratories, which allow storage and analysis of very large information sets. Bio-computing is therefore gradually becoming one of the most important features in laboratories.

For scientists and researchers of today, bio-computing becomes more and more of a hot topic. In a market where the cycle of biomarker-research and discovery must be fast and reliable in order for the biotech companies to be able to compete and to survive, the time-tomarket for drugs and diagnostic tools must be shortened.

New high throughput technologies like DNA sequencers, Micro Arrays, Mass Spectrometry and Protein Arrays have dramatically accelerated the process of collecting biological data and shifted the bottleneck in the drug discovery process from the lack of biological data to analysis of this overflow of biological data. Few approaches have however been reported for the data analysis problems specifically targeted on SELDI-TOF mass spectrometry data.

For more information visit: www.medicwave.com

About Medicwave

MedicWave is a software company that develops cutting edge bioinformatics tools in close collaboration with strategic partners both within academia and pharma / biotech. MedicWave is engaged in the business of Bioinformatics software / Life Science Informatics with focus upon Proteomics.

Advances in information technology bring powerful computational capabilities to laboratories, which allow storage and analysis of very large information sets. Biocomputing is therefore gradually becoming one of the most important features in laboratories.

MedicWave's first product, the Proteinmarker Detection SoftwareTM (PDSTM), was developed for analysing high dimensional proteomic data. Module 1 for PDSTM detects peaks in proteomic data and the module is now available for download with the PDSTM 2.0 software.

MedicWave AB Storgatan 44, S-302 43 Halmstad, Sweden
Tel: +46 (0)709 483 001 Fax: +46 (0)35-100 848
E-mail: info@medicwave.com