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In Vitro Technologies, Inc. (IVT)
and SOLVO Biotechnologies Inc. Announce North American (US and Canada)
Distribution Agreement for Solvo’s in vitro ABC Membrane Transporter Assay
Products
Baltimore, US - Budapest,
Hungary; October 20th, 2005 — In Vitro Technologies, Inc. (IVT) and SOLVO
Biotechnologies Inc. (SOLVO) announced that they have formed a strategic
partnership to distribute SOLVO’s leading in vitro ABC Membrane Transporter
Assay Product Line in the US and Canada.
In Vitro Technologies, Inc. is a recognized leader in providing quality in vitro
products and services, particularly for ADME-Tox research applications.
Continuing with IVT’s commitment to bring an extensive line of solutions for
drug discovery and development research, IVT and SOLVO have collaborated to
leverage IVT’s strength in the marketplace and SOLVO’s innovative Membrane
Transporter products. “We are very excited about this partnership with SOLVO and
firmly believe that it will deliver additional value to pharmaceutical research
customers in North America. By making the products available from with in the
United States, we are making the purchase process efficient and cost-effective
coupled with increased ability to provide technical support.” said Dr. Paul
Silber, President and CEO of IVT.
“By now, it is common knowledge among researchers that ABC transporters play a
key role in the function of the blood-brain barrier (BBB), blood-CSF barrier,
blood-testis barrier, intestinal epithelia (absorption), airway epithelia, liver
epithelia and the kidney epithelia, “ explained Gábor Heltovics, SOLVO’s
Business Development Director. “SOLVO’s leading in vitro assay systems are
designed to detect interaction of test compounds with a wide array of ABC
Transporter proteins found at these vital pharmacological barriers. Our products
are widely used for in vitro ADME/Tox, DMPK, oncology drug research and
multi-drug resistant (MDR) modulating agent discovery. We welcome the
opportunity to work with In Vitro Technologies, Inc. as an ideal partner to
further expand the usage of our products”.
SOLVO’s unique technology platform is built on the following core capabilities:
• Expression of a wide array of human ABC transporters (MDR1, MDR2/3, MRP1,
MRP2, MRP3, MRP4, MRP5, MRP6, MXR, BSEP and others) and rodent (rat, mouse)
transporters in various expression systems (e.g. baculovirus-based insect cell);
• Functional characterization of proteins (ATPase, transport and binding data);
• Identification of new drug targets on ABC transporters.
About In Vitro Technologies, Inc.:
IVT is a privately held corporation, recognized as a market leader in
revolutionizing the drug discovery and development process through specialized
in vitro products and services, with particular emphasis on ADME-Tox
applications. IVT offers primary cell cultures from liver, kidney, and other
organ systems along with microsomes and other sub-cellular fractions. Some of
the key services offered include drug absorption (skin, gastrointestinal),
metabolism (CYP inhibition, CYP induction), target organ toxicity, and
bioanalytical services.
About SOLVO Biotechnology:
SOLVO Biotechnology is a privately held company specializing in R&D and
commercialization of in vitro drug discovery assays, diagnostics and
therapeutics related to Membrane Transport Proteins and Multidrug Resistance in
cancer and other diseases.
SOLVO offers drug discovery products and services to pharmaceutical,
biotechnology and consumer goods industries, relevant to many therapeutic areas
and product categories.
SOLVO Biotechnology provides four different solutions for ABC (xenobiotic)
transporter assays to be used in drug discovery:
• Membrane Preparations – to be used for ATPase Assay and Vesicular Transport
Assay (direct uptake) measurements;
• Fee-For-Service Screening;
• Sublicense for the Calcein Assay;
• Custom-Made Expression and Screening Systems.
CONTACT INFORMATION:
In Vitro Technologies, Inc.
SOLVO Biotechnology Inc.
Lalit Gaur/Randy Kiser
Petra Máriás
1-410-455-1242
36 62 426 098
www.invitrotech.com
www.solvo.hu
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