SUPELCO SIGNS EXCLUSIVE DISTRIBUTION AGREEMENT WITH MIP TECHNOLOGIES

ST. LOUIS, MO, 27th November 2006 – Supelco, a division of Sigma-Aldrich (NASDAQ: SIAL), announced today that it has signed an exclusive global distribution agreement with Lund, Sweden-based MIP Technologies AB. Under the agreement, Supelco will distribute the analytical and preparative Molecularly Imprinted Polymer (MIP) separation products. The Companies will collaborate on the development of new products. MIP Technologies will continue to separately develop its process scale separations business.

These new products contain MIP particles produced by MIP Technologies. MIPs are solid phase polymer materials manufactured with specific affinity for single compounds or classes of compounds. They are applied in pharmaceutical, food & beverage and forensic markets, veterinary institutes, environmental laboratories, and health agencies where they are used in isolating trace compounds from complex matrices.

Currently available MIP products include Solid Phase Extraction (SPE) cartridges for specific analysis of chloramphenicol, tobacco nitrosamine derivatives, triazines, clenbuterol and other beta-agonists, beta-blockers, as well as beta-receptors.

The application of MIP SPE cartridges enables straightforward sample preparation for trace analysis from complex matrices like milk, meat, or urine, resulting in significantly reduced analysis time and costs, increased sensitivity, and improved detection when compared to conventional methods.

“We are very pleased to further strengthen our sample preparation product offering with the addition of this MIP SPE design,” said Dave Julien, President of Sigma-Aldrich Research Specialties business unit. “In combination with our exclusive Solid Phase Micro Extraction (SPME), Flash, and classical SPE technologies, the addition of MIPs are expected to enhance Sigma-Aldrich’s Supelco brand as a strong provider of innovative and unique tools for analytical sciences.”

Anthony Rees, CEO of MIP Technologies, said: “This is a major step forward for our company in realizing its vision to become the number one supplier of MIP-based products. The partnership with Supelco and Sigma-Aldrich, gold standard companies in the separations arena, will create an unmatchable team in the development of selective separations materials. We are really excited by the business opportunities that this relationship will open up.”

About Sigma-Aldrich:

Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 35 countries and has 7,200 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at http://sigma-aldrich.com

About MIP Technologies:

MIP Technologies AB is a world leading company in the development of molecularly imprinted polymers (MIPs). The Company is a pioneer in the commercial applications of MIPs, holds important patents, and maintains cutting-edge research activities in the area. The Company's mission is to provide innovative products based on molecularly imprinted polymers that serve industry's needs in analytical, preparative and process scale 'selective separations'. The Company has environmental permission to produce MIP phases at the 500 kg level and is well placed to develop large-scale separation solutions for its customers. Currently, the Company markets analytical separation products (e.g. SPE) and has multiple custom process scale projects in place with several blue chip companies. MIP Technologies has its headquarters in Lund, Sweden. For more information about MIP Technologies AB visit www.miptechnologies.com

Cautionary Statement:

This release contains forward-looking statements relating to future performance, goals, strategic actions and initiatives and similar intentions and beliefs and other statements regarding the Companies’ expectations, goals, beliefs, intentions and the like, which involve assumptions regarding the Companies’ operations and conditions in the markets the Companies serve. The Companies do not undertake any obligation to update these forward-looking statements.

Media enquiries to Northbank Communications:
Kathryn Robertson, Tel: +44 (0)1260 296506
kj.robertson@northbankcommunications.com

At Sigma-Aldrich:
Sean Battles, Tel: +1-314-286-7616