Fourth New Fluorescence Application of Dyversity Makes Image Analyser Best in Class for 1D and 2D Protein Gel Imaging

October 12th 2006 Cambridge, UK: Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce, Dyversity, its new multi-functional imager can detect nanogram quantities of protein stained with Invitrogen’s Pro-Q Diamond in seconds, providing an excellent method for proteomic researchers who want to rapidly image 1D and 2D protein gels.

Using a Dyversity system fitted with a Cy dye lighting module, dual wavelength transilluminator, UV and Cy3 dye emission filters, Syngene’s technical experts imaged 1D acrylamide gels containing 1000-0.1ng Pro-Q Diamond stained phosphoprotein molecular weight standard, PeppermintStick (Invitrogen). The gel images were captured using two different settings: Cy3 excitation with a Cy3 emission filter and medium-wave UV excitation with a UV emission filter.

Syngene’s application specialists found both imaging conditions of Dyversity produced comparable results with identical exposure times, detecting as little as 5ng of Pro-Q Diamond stained protein in less than 3 seconds. This result coupled with the fact Dyversity can also rapidly detect nanogram amounts of other fluorescent proteomics stains such as Deep Purple, SYPRO Ruby and Flamingo™, as well as traditional visible stains including Coomassie Blue, means the Dyversity system is an excellent, cost-effective alternative to laser scanning for imaging a variety of protein stained gels.

Laura Sullivan, Syngene’s Divisional Manager explained: “We have designed Dyversity 6 to include a high resolution 6.3 mega pixel CCD camera so that unlike a laser scanner the system can simultaneously excite at the optimum fluorescent or visible light excitation peak across an entire gel, making image acquisition a task that takes seconds rather than minutes. Additionally, since Syngene has determined the optimal imaging conditions for detecting small quantities of protein stained with Pro-Q Diamond and a range of many other common protein dyes, Dyversity is fast becoming the perfect system for gel based proteomics research.”

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For Further Information Contact:
Jayne Arthur, Syngene, Beacon House, Nuffield Road, Cambridge, CB4 1TF, UK.
Tel: +44(0) 1223-727123 Fax +44 (0) 1223-727101
Email: jayne.arthur@syngene.com  Web site: www.2dymension.com 

Editor Contact:
Dr Sue Pearson, PO Box 170, Hitchin, Hertfordshire SG5 3GD, UK.
Tel/Fax + 44(0) 1462-635327 Email: sue6.pearson@ntlworld.com

Note to Editors

About Syngene

Syngene is a world-leading supplier of integrated imaging solutions for analysis and documentation of gel-based information. Syngene’s systems are used by more than 10,000 research organisations and over 50,000 individual scientists worldwide and include many of the world’s top pharmaceutical companies and major research institutes.

Syngene, founded in 1997 is a division of the Cambridge based Synoptics Group. The Group’s other divisions, Syncroscopy and Synbiosis, specialise in digital imaging solutions for microscopy and microbial applications respectively. Synoptics currently employs more than 50 people in its UK and subsidiary operation in Frederick, USA.