TTP LabTech combines microplate cytometer with Invitrogen reagents to maximise
HCS parameters
Acumen® eX3 speeds up cytotoxicity profiling
Royston, GB, 14 May 2009 – TTP LabTech has today announced a number of
high throughput platform solutions for the study of cytotoxicity. The
platforms utilise the successful Acumen® eX3 fluorescence microplate cytometer
and a number of new solutions for toxicity profiling developed by Invitrogen,
a division of Life Technologies Corporation. This announcement comes at a time
when such cellular based assays are being increasingly recommended as the
first approach in determining drug on- and off- target effects.

The Acumen® eX3 laser scanning cytometer is an ultra-high throughput system
for cell-based screening that offers enhanced multiplexing capability to
maximise data content and the rapid generation of robust data sets when
deployed with ready-to-use Molecular Probes® kits and reagents from Invitrogen.
With these robust Molecular Probes® high-content screening products, a number
of cytotoxic phenomena can be analysed including: cell viability, Dna damage
and cell cycle processes such as mitosis. The strength of the Acumen® eX3
platform combined with these robust Invitrogen high content screening (HCS)
products enables the high-throughput analysis of a wide variety of toxicity
parameters.
Dr Paul Wylie, Acumen Product Manager, TTP LabTech, commented “The synergies
between TTP LabTech’s analysis technologies and Invitrogen’s HCS reagents are
fully exploited by these developments through the partnering of Acumen® eX3’s
class-leading multiplexing performance with novel reagents of broad
applicability”.
END
Editors’ notes
About TTP LabTech Ltd
Based near Cambridge, UK, TTP LabTech is part of TTP Group plc, one of the
world's most successful technology companies. TTP LabTech’s mission is to
provide practical and innovative solutions in the pharmaceutical and
healthcare industries by combining the best science with first-rate
engineering. TTP LabTech’s products are designed to increase efficiency,
effectiveness, flexibility or overall capability in key biopharmaceutical
research processes including compound storage (comPOUND®), low volume liquid
handling (mosquito®) and fluorescence detection (Acumen eX3).
For additional information on TTP LabTech, please visit
www.ttplabtech.com .
Molecular Probes is registered trademark of Invitrogen and Life Technologies
Corporation.
-end-
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