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Thermo Fisher Scientific Launches Micronucleus BioApplication for High
Content Screening at SBS 2008
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The Thermo Scientific Cellomics® Micronucleus v3.0 BioApplication
enables for rapid, automated assessment of gene toxicity
ST LOUIS, MO., (April 6, 2008) — Thermo Fisher Scientific Inc., the world
leader in serving science, today unveiled at SBS, the Thermo Scientific
Cellomics Micronucleus v3.0 BioApplication — a new solution that uses a
cell-based approach for a comprehensive assessment of genotoxicity. This new
introduction not only strengthens the Thermo Fisher Scientific portfolio of
leading-edge high content screening (HCS) products but more importantly allows
the automatic detection of micronuclei formation, providing scientists with a
more productive method for screening compounds earlier in the drug-discovery
process.
The Micronucleus BioApplication relies on the industry-leading Thermo Scientific
Cellomics ArrayScan® VTI system, which comprises high-content screening
instrumentation, informatics and reagent products, allowing researchers to more
rapidly test multiple compounds to discover potential toxic effects on genetic
material. This application provides a more reproducible, method for compound
screening at substantially lower labor costs than traditional manual approaches
to micronuclei quantification.
Micronucleus formation is a strong indicator of genetic toxicity caused by
drug-candidate compounds or environmental toxins. Existing in vitro assays for
micronuclei induction are time-consuming, labor-intensive (requiring several
trained personnel) and can be subjective. Because of these constraints, it has
been virtually impossible to efficiently test large numbers of compounds for
this important indicator of genotoxicity. With the launch of the new Cellomics
Micronucleus v3.0 BioApplication, more cell lines can be tested with more
industry standard assay configurations. This flexibility enables screening for
indicators of genetic toxicity earlier in the development of therapeutic
candidates and improves attrition rates, increasing efficiency and significantly
reducing costs for pharmaceutical companies.
The Micronucleus BioApplication, along with a selection of Thermo Scientific HCS
products, can be seen at the Thermo Scientific product booth (#1613), Society
for Biomolecular Sciences (SBS) conference and exhibition, St Louis, 2008.
Thermo Scientific is part of Thermo Fisher Scientific, the world leader in
serving science.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving
science, enabling our customers to make the world healthier, cleaner and safer.
With annual revenues of $10 billion, we have more than 30,000 employees and
serve over 350,000 customers within pharmaceutical and biotech companies,
hospitals and clinical diagnostic labs, universities, research institutions and
government agencies, as well as environmental and industrial process control
settings. Serving customers through two premier brands, Thermo Scientific and
Fisher Scientific, we help solve analytical challenges from routine testing to
complex research and discovery. Thermo Scientific offers customers a complete
range of high-end analytical instruments as well as laboratory equipment,
software, services, consumables and reagents to enable integrated laboratory
workflow solutions. Fisher Scientific provides a complete portfolio of
laboratory equipment, chemicals, supplies and services used in healthcare,
scientific research, safety and education. Together, we offer the most
convenient purchasing options to customers and continuously advance our
technologies to accelerate the pace of scientific discovery, enhance value for
customers and fuel growth for shareholders and employees alike. Visit
www.thermofisher.com.
Contact:
Scientific Instruments
Jeanette Minshall, Thermo Fisher Scientific
+1 905 332 2000 Ext 319
jeanette.minshall@thermofisher.com
www.thermofisher.com
Media Contact Information:
Secondary Contact Information:
Clare Russell, Alto Marketing
+44 (0)1489 557672
clarer@alto-marketing.com
www.alto-marketing.com
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