Handbook of Pharmaceutical Additives

The Handbook of Pharmaceutical Additives, 3rd Edition describes more than 5,300 trade name products and 4,000 generic chemicals and materials, available from worldwide manufacturers, that function as pharmaceutical additives. Pharmaceutical additives are defined in this reference as secondary ingredients present in both prescription and over-the-counter drug formulations and contributing in one or more of the following ways:

# Improving consumption ease of the dosage form by masking unpleasant odor, improving palatibility or appearance of the active ingredient.

# Enabling or enhancing the delivery of the drug or medicine that is available in a variety of dosage forms (i.e., oral; topical, ophthalmic, and otic; suppositories; injectables; inhalants) and thus improving its efficacy, control of bioavailability, uniformity, and/or flow characteristics

# Increasing the stability of active ingredients

# Acting as a filler or diluent so that an adequate amount of material is available to properly fill a dosage form

# Acting as an antimicrobial or antioxidant to extend the shelf life of the active ingredient

Thus, the definition of pharmaceutical additives for the purpose of this work encompasses excipients, synergists, or chemicals that substantively contribute to the effectiveness of the active ingredient. Entries for both trade names and chemicals contain extensive information gathered from worldwide manufacturers, distributors, trade journals, government documents, and other reference sources.

Target information on components by:

Trade Name • Chemical Name • Synonym • Function • Application • CAS Number • EINECS Number • FEMA Number • Manufacturer

Coverage includes Pharmaceutical Additive chemicals that function as:

Absorbents/Adsorbents · Acidulents/Buffer/pH adjuster/Neutralizers · Aerosols/Propellants · Anticaking agents Anticoagulants · Antigellant · Anti-inflammatory agents/Antiphlogistic agents · Antimicrobials · Antioxidants · Astringents · Bases · Chelating agent/Sequestrants · Coagulants · Coating agents · Colorant/Color enhancers/Dyes/Pigments · Complexing agent · Conditioners · Controlled release agent · Crystal growth Regulators · Denaturants · Dessicant/Drying agents/Dehydrating agents · Dietary Supplements · Dispersants · Emollients · Emulsifiers · Encapsulants · Enzymes · Fillers/Extenders/Diluents/Excipients · Flavor/Flavor enhancers · Flow aids · Fragrances/Perfumes/Aromatics · Gellants · Hardeners/Stiffeners · Humectants Lubricants · Moisturizer · Nutritive fortifiers · Odor masking agents · Opacifiers · Permeation enhancers · Plasticizers · Protective agents/Soothing agents/Demulcents · Solvents · Spreading agents · Stabilizers · Superfatting agents Sweeteners · Synergists · Tablet binders · Tablet disintegrants · Tabletting aids · Tonicity agents · UV absorbers · Vehicles/Carriers · Viscosity modifier · Water repellants · Wetting agents

In these Application Areas:

Orals:Tablets, Capsules, Syrups/Liquids/Suspensions Topicals: Ointments/Creams/Lotions/Gels Suppositories · Ophthalmics · Otics · Injectables · Inhalants

Publication date: April 2007

Pages:1200

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