Optimizing Synthetic RNAi - Perspectives from the Pharmaceutical and Biotech Industry

RNA interference (RNAi) has rapidly evolved into a powerful technique to silence gene expression in cells allowing researchers to study the molecular effects of modulating expression at the level of individual genes. The diversity of its applications has made RNAi an indispensable tool for both academic and industrial scientists interested in gene function characterization, signaling pathway analysis, and target validation.

From the perspective of industrial scientists who use synthetic siRNA, this report will:

> Identify the RNAi research objectives of pharmaceutical and biotech scientists;

> Present siRNA customer purchasing preferences by key experimental design parameters;

> Examine future research trends in nucleic acid-based gene silencing;

> Determine industrial throughput levels of synthetic siRNAs per target gene;

> Assess market growth potential for custom, pre-designed, and validated synthetic siRNAs;

> Reveal preferred suppliers of synthetic siRNAs and their Net Promoter Score rankings;

Determine synthetic siRNA brand share by usage rates and relative expenditure for the U.S. market and the rest of the world market;

> Understand the role of customer satisfaction and brand loyalty in the purchasing decision;

> Provide insights into which product attributes contribute to customer satisfaction and customer dissatisfaction; and

> Evaluate brand health of the top suppliers based upon key performance metrics related to product promotion, product attractiveness, product price, product placement and supplier customer service and technical support.

Publication Date: December 2006 Page Count: 150

Price