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    BioPortfolio | Datamonitor Reports |  Pipeline Insight: Hematological Malignancies Companies target niche indications to facilitate market entry

    Pipeline Insight: Hematological Malignancies  Companies target niche indications to facilitate market entry

    Pipeline Insight: Hematological Malignancies Companies target niche indications to facilitate market entry


    There are 224 different pipeline products in clinical development for hematological malignancies. Twenty-three (10%) of these drugs are in late-phase studies and are forecast to achieve peak sales of $3.5 billion in 2018. Drug developers are keen to replicate the success of the two blockbusters: Biogen Idec/Genentech/Roche's Rituxan (rituximab) and Novartis's Gleevec (imatinib).
  • Epidemiology of the hematological malignancies split by disease subtype, covering the seven major markets as well as the top 5 rest of world markets
  • Overview of the current treatment options for leukemia, lymphoma, multiple myeloma and myelodysplastic syndromes with identification of unmet needs
  • Examination of the late-phase hematological malignancies pipeline, key company market strategies and opportunities for drug developers
  • Pipeline insight based on qualitative interviews with key opinion leaders in the field of hematological malignancies
  • There are 13 molecular-targeted therapies, six immunotherapeutic agents and four cytotoxic agents in late-phase clinical development for hematological malignancies. Immunotherapeutic agents are forecast to achieve the highest class sales of $1.7 billion in the seven major markets by 2018.

    Pipeline agents holding the greatest commercial potential include the immunoconjugated monoclonal antibodies Arzerra (ofatumumab; Genmab/GlaxoSmithKline), galiximab (Biogen Idec) and lumiliximab (Biogen Idec), as well as the cytotoxic agent pixantrone (Novartis).

    Smaller, niche indications are increasingly attracting R&D interest as a result of the high unmet needs that persist in a number of hematological malignancy subtypes. At least 9 (39%) of the 23 late-phase pipeline agents are targeting patient sub-populations to potentially fill gaps in the market and facilitate launch.
  • Acquire a detailed appreciation and impartial perspective of the entire hematological malignancies developmental pipeline
  • Identify the key products in late-phase development based on sales forecasts to 2018 and Datamonitor's drug assessment methodology
  • Assess how the future treatment of many hematological malignancies will incorporate pipeline products

  • Publication: 39904
    Library Code: DMHC2507
    Type: Report
    Format: PDF & SlidePack & DataPack
    Pages: 373


    Table of Contents
    Price: $11,400.00 / €7,619.76



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