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BioPortfolio | BioInformant Reports | Poly(ADP-ribose) polymerase (PARP) Research Products

Poly(ADP-ribose) polymerase (PARP) Research Products

Poly(ADP-ribose) polymerases (PARPs) are a superfamily of 18 proteins, of which PARP-1 is the best characterized. PARPs are enzymes that are activated by DNA breaks to facilitate DNA repair

Currently, there is a great deal of research being done on PARP, because its activity is linked to serious disease conditions, including cancer, ischemia, diabetes, arthritis, inflammatory bowel disease, and septic shock. Of greatest therapeutical interest are PARP-1 inhibitors, as they exert a duel effect of inhibiting cell death and reducing inflammation. Indeed, PARP inhibitors have been shown to be effective as radiation-sensitizing agents and appear promising in the treatment of conditions involving oxidative stress. Additionally, quantification of PARP activity and identification of abnormal patterns of PARP degradation by proteases might have utility in the diagnosis various conditions.

At this time, there are a limited number of PARP research products available to the research community. Commercially available research tools include enzymes, antibodies, inhibitors, and assay kits designed for the measurement of PARP activity. Because of the size and growth potential of the PARP research products market, providing products to this market niche represents a significant financial opportunity. This report is an in-depth exploration of the PARP research products market, including market conditions, dominant competitors, clinical applications, and product opportunities available to companies interested in this lucrative, early-stage market.

December 2008 PDF
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Price: $3,495.00 / €2,338.16

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