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BioPortfolio | Business Insights | The Future of Biobanks: Regulation, ethics, investment and the humanization of drug discovery

The Future of Biobanks: Regulation, ethics, investment and the humanization of drug discovery

The Future of Biobanks’ is a report published by Business Insights that examines major trends in the biobanking industry and identifies the key initiatives to upgrade the biobanking infrastructure. This report explores the applications of biobanks and provides examples of how large sets of high-quality biosamples are creating new ways to diagnose, prevent and treat diseases. The activities of over 180 US biobanks are assessed to illustrate how the scale and scope of biobanking is changing. This report also evaluates the limitations of biobanks, in addition to reviewing the unique legal, regulatory and ethical issues that surround this new frontier of biomolecular research.

Key Findings

• A number of new, high-quality biobanks will accelerate the development of personalized diagnostics and therapeutics over the next decade.

• Increased co-operation between biobanks can advance this progression, although many scientific and political barriers must be overcome.

• An estimated $1bn has been invested in the biobanking industry within the last ten years. The first advances are expected to result in the improved treatment of cancer, and progression for a range of other common diseases will follow.

• Recently established biobanks have reached unprecedented levels of scale, particularly the Taizhou project in China. Studies conducted on the entire population of a country may soon be possible.

• At least 179 biobanks with 345,000 donors exist in the US, most of which were established in the last 10 years.

• As biotechnology companies’ biobanking assets mature in terms of the number of samples collected their R&D productivity and the number of products available for outsourcing will increase

Use this report to...

• Assess the strengths and limitations of biobanks and understand their scientific and commercial relevance with this report’s analysis of biobank-enabled targeted therapeutics and diagnostic/prognostic tests.

• Analyze growth in disease-based biobanks by using this report’s unique review of 180 US-based biobanks by disease type and gain insights into the collaborative networks that can leverage greater sample sizes.

• Evaluate major founder/national population biobanks and gain insights into private sector biobanking with this report’s examination of contract service providers, biomarker discovery companies, pharma collections and research collaborations.

• Review developments in the regulatory framework for biobanking and understand ethical issues including informed consent, withdrawal and ownership, confidentiality and commercialization.

Explore issues including...

• Biobanking expansion. The falling cost of genomic technologies is expanding the scale and scope of biobanking research. This has already resulted in the development of several new diagnostic tests that can improve risk assessment and treatment decisions.

• Potential for personalised medicine. Very few personalized medicines exist, but the creation of large sets of high-quality biosamples should widen the clinical application of new personalized products and services.

• Legal and ethical issues. Although the legal and ethical frameworks that govern biobanking are still evolving, many major issues such as ownership and commercialization are now largely addressed during the consent process.

• Cost of national biobanks. National biobanks have been established in several countries, although their value has been questioned. Conducting large-scale population studies requires significant investment, due to the extremely large collections of biosamples and data involved (including relevant medical history, lifestyle and environmental information).

Discover...

• Why are biobanks a critical resource?

• Which types of biobank are most common?

• What are the most common disadvantages of biobanks?

• Which major drug developers have invested in biobanks?

• What are the major uncertainties surrounding the future of biobanks?

• What growing trend could boost biobanking?

• When will the benefits of biobanking be realized?

PDF March 2009
Table of Contents
Price: $3,835.00 / €2,565.62

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