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BioPortfolio | Beachhead Reports | The Future of Genomic Research Emerging Markets and Applications for Microarray Technology

The Future of Genomic Research Emerging Markets and Applications for Microarray Technology

Microarrays for gene expression have made a profound impact in the biomedical world. The next obvious step is to go beyond gene expression and utilize microarray technology to enable whole ‘ome’ analysis for a variety of other applications, such as genotyping, comparative genomic hybridization, splice variants, ChIP arrays, and resequencing.

Mitochondrial DNA and protein expression microarrays provide invaluable information in both the research and clinical setting. From a pharmaceutical and biotechnical perspective, microarrays can assist in target identification, biomarker discovery and validation, patient stratification and therapeutic monitoring to name a few examples.

Diagnostic products are being realized through the discovery and implementation of various microarray technologies. From the clinical perspective, microarrays are helping to diagnose many genetic disorders, such as cystic fibrosis, and will hopefully aid in finding therapeutic interventions. The field of oncology has benefited greatly with the advent of genomic microarrays. Genetic modifications such as insertions and deletions

and signal transduction pathway analysis are providing researchers with valuable information into the cause and effect of many different types of cancers, leading to appropriate diagnoses and treatment.

This report discusses the current uses of microarray technology, including gene expression, and discuss the commercial opportunity for these technologies, given pharmaceutical and diagnostic objectives and trends. Detailed market projections and analysis are based on direct feedback from key industry leaders in genomics.

About the Authors

Olivia Scaros graduated from the University of Illinois in 1988 with a Doctor of Pharmacy degree. She has been employed by various pharmaceutical firms, including Sandoz Pharmaceuticals, Bayer Corporation, and Pfizer Inc., both as an employee and a consultant. For the past 13 years, Dr. Scaros’ main focus has been medical writing, including study reports, clinical protocols, articles, and other projects for the pharmaceutical industry.

Richard Fisler is a partner with Beachhead Consulting (www.beachhead.com), a firm specializing in technology evaluation, strategic planning, and market assessment in the life science industry. Prior to his work at Beachhead, he brought a wide variety of high-technology platforms to market through positions in the microarray and live-cell microscopy industries. Additionally, he has spent 11 years in management and engineering in the medical imaging field.

Olivia Scaros, PharmD, Richard Fisler, and Gary Sams, Ph.D. Beachead Consulting, June 2007 Format PDF
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