Vaccines 2009: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry

Vaccines 2009: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry
CHAPTER ONE: EXECUTIVE SUMMARY
  • THE GLOBAL VACCINES INDUSTRY
  • Scope And Methodology
  • Overview
  • Pediatric Preventative Vaccines
  • The Market
  • Adult Preventative Vaccines
  • The Market
  • Total Market
  • Issues and Trends
CHAPTER TWO: INTRODUCTION TO VACCINES
  • A Brief History: The Development of Vaccines
  • The Immune Response
  • Mechanism of Action
  • Types of Vaccines
  • Attenuated (Weakened) Live Viruses
  • Killed (Inactivated) Viruses
  • Toxoid Vaccines
  • Genetically Engineered/Modified Vaccines
  • Subunit Vaccines
  • Conjugate Vaccines
  • DNA Vaccination
  • Vaccine Approval Process
CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES
  • Introduction
  • Childhood Immunization in the United States
    • Childhood Immunization Rates
    • Challenges to the Vaccine Delivery System
    • Recommended Childhood Immunization Schedule
    • State Immunization Recommendations
  • Pediatric Vaccine Products
    • BCG
    • Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio
    • Diphtheria
    • Pertussis
    • Tetanus
    • Hepatitis B
    • Poliomyelitis
    • Enterotoxigenic Escherichia coli
    • Haemophilus Influenzae Type B
    • Hepatitis A
    • Measles, Mumps and Rubella
    • Measles
    • Mumps
    • Rubella
    • Meningococcal Disease
    • Parainfluenza Virus Type 3
    • Pneumococcal Conjugate
    • Respiratory Syncytial Virus
    • Rotavirus
    • Varicella
  • Pediatric Vaccines in Development
    • Global Initiatives for Vaccine Research
  • Cost of Vaccines in the United States
  • The World Market for Pediatric Preventive Vaccines
    • Total Market Size and Forecast
    • Hepatitis Vaccine Market
    • Market Analysis
    • Leading Products and Competitors
    • Haemophilus Influenzae Type B Vaccine Market
    • Market Analysis
    • Leading Products and Competitors
    • Measles, Mumps and Rubella Vaccines
    • Market Analysis
    • Combination Vaccines Market
    • Market Analysis
    • Leading Products and Competitors
    • Pneumococcal Vaccine
    • Leading Products and Competitors
    • Poliovirus Vaccine
    • Market Analysis
    • Leading Products and Competitors
    • Varicella Vaccines
    • Market Analysis
    • Leading Products and Competitors
    • Other Vaccines Market
    • Market Analysis
    • Leading Products and Competitors
CHAPTER FOUR: ADULT PREVENTIVE VACCINES
  • Introduction
  • Adult Vaccine-Preventable Diseases: Facts and Figures
  • Global Virological Surveillance Program
  • Recommendations for Adult Immunizations
  • WHO International Health Regulations
  • Adult Vaccine Products
    • Allergy
    • BCG
    • Cancer
    • Cervical Cancer
    • Cholera
    • Diphtheria-Tetanus
    • Helicobacter Pylori
    • Hepatitis
    • Hepatitis A
    • Hepatitis B
    • Hepatitis C
    • Hepatitis D
    • Hepatitis E
    • Herpesvirus
    • HIV/AIDS
    • Influenza
    • Japanese Encephalitis
    • Leishmaniasis
    • Malaria
    • Pneumococcal Disease
    • Rabies
    • Shingles
    • Tuberculosis
    • Typhoid Fever
    • West Nile Virus
    • Yellow Fever
  • Adult Vaccines in Development
  • Global Initiatives for Vaccine Research
  • The World Market for Adult Preventive Vaccines
    • Total Market Size and Forecast
    • Cervical Cancer Market
    • Market Analysis
    • Leading Products and Competitors
    • Hepatitis Market
    • Market Analysis
    • Leading Products and Competitors
    • Influenza Vaccine Market
    • Market Analysis
    • Leading Products and Competitors
    • Market Analysis
    • Leading Products and Competitors
    • Travel, DT, and Miscellaneous Vaccine Market
    • Market Analysis
    • Leading Products and Competitors
CHAPTER FIVE: VACCINES MARKET SUMMARY
  • Trends Driving the Vaccines Market
  • Market Size and Forecast
  • Vaccine Market Competitors
  • Pediatric Vaccines
  • Major Manufacturer’s Market Share
  • Adult Vaccines
  • Major Manufacturer’s Market Share
CHAPTER SIX: ISSUES AND TRENDS
  • Vaccine Safety
    • Refusal to Immunize
    • Post-Licensure Surveillance
    • Vaccine Adverse Event Reporting System
    • The Vaccine Safety Datalink Project
    • Phase IV studies
    • The Vaccine Injury Compensation Program
    • World Health Organization
    • Other Initiatives
    • The Future of Vaccine Safety
  • Vaccine Shortages
    • Preventing Shortages in the Developed Countries
    • Financial incentives
    • Equitable pricing
    • Vaccine stockpiles
    • Preventing Shortages in Developing Nations
    • Vaccine bonds
  • Economic Effects
    • Industrialized Nations
    • Developing Nations
  • Preventing Pandemics
    • U.S. National Vaccine Plan
  • Vaccines and Bioterrorism
  • Overview
  • Project Bioshield Act of 2004
  • National Bio and Agro-Defense Facility
  • Vaccine Treatment and Evaluation Units
  • Anthrax
  • Smallpox
  • Plague
  • Botulism
  • Tularemia
  • Viral Hemorrhagic Fevers
  • DNA Vaccination
  • Innovations in Vaccine Delivery Systems
    • Edible Vaccines
    • Mucosal Delivery
    • Intranasal Delivery
    • Vaccine Patches
    • DTC Advertising
CHAPTER SEVEN: COMPANY PROFILES
  • Acambis plc
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • AlphaVax, Inc.
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Bavarian Nordic A/S
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Baxter Healthcare
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Celldex Therapeutics
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Crucell
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Emergent Biosolutions
    • History and Lines of Business
    • Strategic Acquisition and Alliance
    • Vaccine Products
    • Financial
  • GlaxoSmithKline
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Medimmune
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Merck & Co. Inc
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Nabi Biopharmaceuticals
    • History and Lines of Business
    • Strategic Alliance
    • Vaccine Products
    • Financial Information
  • Novartis
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
    • History and Lines of Business
    • Strategic alliances
    • Vaccine products
    • Financial Information
  • Pharmexa
    • History and Lines of Business
    • Strategic alliances
    • Vaccine Products
    • Financial Information
  • Sanofi Pasteur
    • History and Lines of Business
    • Strategic Alliances
    • Vaccine Products
    • Financial Information
  • Wyeth
    • History and Lines of Business
    • Vaccine Products
    • Financial Information
APPENDIX: COMPANY DIRECTORY LIST OF EXHBITS CHAPTER ONE: EXECUTIVE SUMMARY
  • Figure 1-1: World Market for Pediatric Vaccines 2004-2013
  • Figure 1-2: World Market for Adult Vaccines 2004-2013
CHAPTER TWO: INTRODUCTION TO VACCINES

  • Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2008

  • Table 2-2: Vaccine-Preventable Diseases, April 2009

  • Table 2-3: VAERS Table of Reportable Events Following Vaccination

  • Table 2-3 (cont.): VAERS Table of Reportable Events Following Vaccination

CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES

  • Table 3-1: Global Immunization Rates by Vaccine Type 2007

  • Table 3-2: Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by Disease 2000-2007

  • Table 3-3: U.S. Recommended Immunization Schedule for Children Ages 0 Through 6 Years, 2009

  • Table 3-4: U.S. Recommended Immunization Schedule for Adolescents Ages 7 to 18 Years, 2009

  • Table 3-5: Selected Pediatric Vaccines in Development, April 2009

  • Table 3-6: World Market for Pediatric Vaccines by Type (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others) 2004-2013 Revenues (in millions)

  • Figure 3-1: Market Share of Pediatric Vaccines by Type 2008 (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)

  • Figure 3-2: Market Share of Pediatric Vaccines, by Type 2013 (DTaP/DTP, Hep, HiB, MMR, Combos, Pneumococcal, Polio, Varicella, Others)

  • Table 3-7: World Pediatric Hepatitis Vaccine Market 2004-2013

  • Table 3-8: World Hib Vaccine Market, 2004-2013

  • Table 3-9: World MMR Vaccines Market 2004-2013

  • Table 3-10: World Combination Vaccines Market 2004-2013

  • Table 3-11: World Pediatric Pneumococcal Vaccine Market 2004-2013

  • Table 3-12: World Poliovirus Vaccine Market 2004-2013

  • Table 3-13: World Varicella Vaccine Market 2004-2013

  • Table 3-14: Other Vaccines Market 2004-2013

CHAPTER FOUR: ADULT PREVENTIVE VACCINES

  • Table 4-1: Universal Adult Immunization Schedule 2009

  • Table 4-2: Adult Immunization Schedule for Populations with Special Medical Conditions, 2008

  • Table 4-3: Initiatives to Require HPV Vaccination by U.S. State, 2009

  • Table 4-4: WHO Pandemic Classification Schedule

  • Table 4-5: Selected Adult Preventive Vaccines in Development, 2009

  • Table 4-6: World Market for Adult Preventive Vaccines by Type (Hepatitis, Influenza, Pneumococcal, Travel/DT/Misc.), 2004-2013 Revenues (in millions)

  • Figure 4-1: Market Share of Adult Vaccines, by Type, 2009

  • Figure 4-2: Market Share of Adult Vaccines, by Type, 2013

  • Table 4-7: World Cervical CancerVaccine Market 2004-2013

  • Table 4-8: World Hepatitis Vaccine Market 2004-2014

  • Table 4-9: World Influenza Vaccine Market 2004-2013

  • Table 4-10: CDC Goal to Double Flu Immunization by 2010 Group and Estimated Immunization Rate (2000 vs 2010)

  • Table 4-11: 2007 Estimated Population by Region and Selected Age Group (in millions)

  • Table 4-12: World Pneumococcal Vaccine Market 2004-2013

  • Table 4-13: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market 2004-2013

CHAPTER FIVE: VACCINES MARKET SUMMARY

  • Figure 5-1: Sales Growth of Vaccines vs. Pharmaceuticals 2004-2013

  • Figure 5-2: World Market for Vaccines by Type 2004-2013

  • Table 5-1: The World Vaccines Market by Vaccine Type 2004-2013 Revenues (in millions)

  • Figure 5-3: World Market for Vaccines Share by Type, 2004, 2008 and 2013

  • Table 5-2: Major Manufacturers’ Shares of the World Vaccine Market, 2008

  • Figure 5-3: 2008 World Vaccines Market Share, by Leading Competitors

  • Table 5-3: Major Manufacturer’s Shares of the World Pediatric Vaccine Market 2008

  • Figure 5-5: Market Share of Pediatric Vaccines Market, 2008

  • Table 5-4: Major Manufacturer’s Shares of the World Adult Vaccine Market 2008

  • Figure 5-6: Market Share of Adult Vaccines Market 2008

CHAPTER SIX: ISSUES AND TRENDS

  • Table 7-1: Selected Companies/Laboratories Developing Biodefense Vaccines