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EXECUTIVE SUMMARY Acute Wounds Burns Chronic Wounds Products Used in Advanced Wound Management Film Dressings Hydrocolloid Dressings Foam dressings Alginate Dressings Hydrogels Non-Adherent Dressings Anti-Microbial Dressings Wound Cleansers and Debriding Agents Skin Replacements and Substitutes Pharmacological Products Physical Therapies The Market The Industry
Section 1: BACKGROUND
1.1 Industry Structure 1.2 A Complex Industry 1.3 Major Wound Management Corporations 1.4 Historical Perspective and Technology Breakthroughs 1.5 World-Wide Regulatory and Reimbursement Environment 1.5.1 Cost Effectiveness 1.5.2 Clinical 1.5.3 Regulatory 1.5.4 Reimbursement 1.5.4.1 U.S.A. 1.5.4.2 European Union 1.5.4.3 France 1.5.4.4 Germany 1.5.4.5 United Kingdom 1.5.4.6 Italy 1.5.4.7 Belgium 1.5.4.8 Spain 1.5.4.9 Scandinavia 1.6 Geographical Differences in Treatments of Wounds 1.7 Minimally Invasive Surgery: Impact on Wound Incidence and Prevalence 1.8 Wound Management Trends 1.8.1 Surgical Wounds 1.8.2 Traumatic Wounds 1.8.3 Burns 1.8.4 Chronic Wounds 1.9 Market Dynamics
Section 2: CLINICAL BACKGROUND AND CASELOAD
2.1 Background 2.1.1 A few Figures 2.1.2 Overview of Functions 2.1.3 Skin Anatomy: A Summary 2.2 Types of Wounds 2.2.1 Classification By Severity 2.2.2 Classification By Morphology 2.2.3 Classification By Etiology 2.2.4 Color Classification 2.3 Surgical Wounds 2.4 Traumatic Wounds 2.5 Burns 2.5.1 Debridement 2.5.2 Grafting 2.6 Pressure Ulcers 2.6.1 Ulcer Classification 2.6.2 Hospital-Acquired Ulcers 2.6.3 Management of Pressure Ulcers 2.7 Venous Ulcers 2.8 Arterial Ulcers 2.9 Diabetic Ulcers 2.9.1 Prevalence 2.9.2 Stages of Diabetic Ulcer 2.9.3 Treatment 2.9.3.1 Amputations 2.9.3.2 Abnormal Scarring 2.9.4 Acquired Immunodeficiency Syndrome 2.10 Wound Healing Physiology 2.10.1 Inflammatory Phase 2.10.2 Proliferative Phase 2.10.2.1 Angiogenesis 2.10.3 Maturation Phase 2.11 Factors Affecting Wound Healing 2.11.1 Extrinsic Factors 2.11.2 Mechanical Stress 2.11.3 Debris 2.11.4 Temperature 2.11.5 Desiccation and Maceration 2.11.6 Infection 2.11.7 Chemical Stress 2.11.8 Medication 2.11.9 Other Extrinsic Factors 2.11.10 Intrinsic Factors 2.11.11 Health Status 2.11.12 Age Factors 2.11.13 Body Build 2.11.14 Nutritional Status 2.12 Major Treatment Categories and Regimes 2.13 Incidence of Treatments, Growth Rates and Trends
Section 3: PRODUCTS, TECHNOLOGIES AND MARKETS
3.1 Background 3.2 Film Dressings 3.2.1 Overview 3.2.2 Product Examples 3.2.3 Market and Competitive Activity 3.3 Hydrocolloids 3.3.1 Overview 3.3.2 Product Examples 3.3.3 Market and Competitive Activity 3.4 Foam Dressings 3.4.1 Overview 3.4.2 Product Examples 3.4.3 Market and Competitive Activity 3.5 Alginate Dressings 3.5.1 Overview 3.5.2 Product Examples 3.5.3 Market and Competitive Activity 3.6 Hydrogels 3.6.1 Overview 3.6.2 Product Examples 3.6.3 Market and Competitive Activity 3.7 Non Adherent Dressings 3.7.1 Overview 3.7.2 Product Examples 3.7.3 Market and Competitive Activity 3.8 Antimicrobial Dressings 3.8.1 Overview 3.8.2 Product Examples 3.8.3 Market and Competitive Activity 3.9 Tissue Engineered Products 3.9.1 Overview 3.9.2 Traditional skin grafts 3.9.3 Skin replacements 3.9.4 Product Examples 3.9.5 Market and Competitive Analysis 3.10 Pharmacological Products 3.10.1 Overview 3.10.2 Product Examples 3.10.2.1 Growth Factors 3.10.2.2 Growth factors: background 3.10.2.3 Classification 3.10.2.4 Regranex 3.10.2.5 Other Growth Factors 3.10.2.6 Non-Growth Factor Modulators 3.10.3 Market and Competitive Analysis 3.10.3.1 Growth Factors 3.10.3.2 Non-Growth Factor Stimulants 3.10.3.3 Gene Therapy 3.11 Physical Treatments 3.11.1 Negative Pressure Devices 3.11.2 Positive Pressure Devices 3.11.3 Mechanically-assisted Wound Closure 3.11.4 Other Physical Wound Therapies 3.11.4.1 Hydrotherapy 3.11.4.2 Electrical Stimulation 3.11.4.3 Electromagnetic Stimulation Devices 3.11.4.4 Ultraviolet Therapy 3.11.4.5 Hyperbaric Oxygen Therapy 3.11.4.6 Ultrasound Devices 3.11.4.7 Laser Devices 3.11.4.8 Wound Imaging/Documentation 3.11.5 Market and Competitive Analysis 3.11.5.1 Pressure Relief Devices 3.11.5.2 Hydrotherapy 3.11.5.3 Electrical Stimulation 3.11.5.4 Hyperbaric Oxygen Therapy
Section 4: Country Market Analysis
4.1 Global Overview 4.2 Market Estimates 4.2.1 Market Potential 4.2.2 Leading Wound Care Companies 4.2.3 Leading National Markets 4.3 USA 4.3.1 Market Opportunity 4.3.2 Market for Advanced Wound Management Products 4.4 Japan 4.4.1 Wound Care Market 4.4.2 Market Opportunity 4.4.3 Leading Companies 4.5 Germany 4.5.1 Wound Care Market 4.5.2 Leading Companies 4.6 France 4.6.1 Wound Care Market 4.6.2 Leading Companies 4.7 Italy 4.7.1 Wound Care Market 4.7.2 Leading Companies 4.8 United Kingdom 4.8.1 Wound Care Market 4.8.2 Leading Companies
Section 5: COMPANY PROFILES
5.1 Major Companies 5.1.1 Carrington Laboratories Inc. 5.1.2 Coloplast Group 5.1.2.1 Financials 5.1.3 ConvaTec Inc. 5.1.4 Covidien 5.1.4.1 Kendall 5.1.4.2 Financial data 5.1.5 Derma Sciences Inc. 5.1.5.1 Financials 5.1.6 DeRoyal Industries Inc. 5.1.7 Ethicon (Johnson & Johnson) 5.1.8 Gentell Inc. 5.1.9 Geritrex Corp. 5.1.10 Hartmann Group 5.1.11 Hollister Incorporated 5.1.12 Lohmann and Rauscher International GmbH and Co. KG 5.1.13 Medline Industries 5.1.13.1 Advanced Wound Care Products 5.1.14 3M Group 5.1.14.1 Financial data 5.1.15 Mölnlycke Health Care AB 5.1.16 Smith and Nephew Group 5.1.16.1 Financial data 5.1.17 UDL Laboratories (Mylan Labs.) 5.2 Specialist Companies 5.2.1 Antimicrobial Dressings 5.2.1.1 Acrymed Inc. 5.2.1.2 Argentum Products LLC 5.2.1.3 Microban International Ltd 5.2.2 Oxygen Therapy 5.2.2.1 Perry Baromedical Corp. 5.2.3 Tissue Regeneration 5.2.3.1 Advanced BioHealing 5.2.3.2 BioTissue Technologies AG 5.2.3.3 Celltran Limited 5.2.3.4 Fidia Group 5.2.3.5 Genzyme Biosurgery 5.2.3.6 Innogenetics 5.2.3.7 Integra Life Sciences Inc. 5.2.3.8 IsoTis S.A 5.2.3.9 Modex Therapeutics 5.2.3.10 Organogenesis Inc. 5.2.3.11 Ortec International Inc. 5.2.4 Negative Pressure Wound Therapy 5.2.4.1 Kinetic Concepts Inc. 5.2.4.2 BlueSky Medical Group (Smith & Nephew) 5.2.5 Growth Factors 5.2.5.1 E.S. Cell International 5.2.6 Electrical Therapies 5.2.6.1 BioMedical Life Systems Inc 5.2.6.2 Diapulse Corp of America 5.2.6.3 Electromedical Products International Inc. 5.2.6.4 Globalcare Medical 5.2.6.5 Microvas Technologies 5.2.7 Odor Control 5.2.7.1 CliniMed 5.2.8 Other Therapeutic Modalities 5.2.8.1 AGT Sciences Ltd 5.2.8.2 Agennix 5.2.8.3 Advanced Medical Solutions Group plc 5.2.8.4 Anodyne Therapy LLC 5.2.8.5 Applied Tissue Technologies 5.2.8.6 Roho Inc. 5.2.9 Summary Profiles 5.2.9.1 AciesHealth 5.2.9.2 Bard Medical Division 5.2.9.3 Biocore Medical Technologies Inc. 5.2.9.4 Biomarin Pharmaceuticals Inc. 5.2.9.5 Brennen Medical Inc. 5.2.9.6 Dermacor Inc. 5.2.9.7 Derma Rite Industries LLC 5.2.9.8 Encelle Inc. 5.2.9.9 Ferris Manufacturing Corp. 5.2.9.10 Fibrogen 5.2.9.11 Geistlich Pharma 5.2.9.12 HemCon Inc 5.2.9.13 Hymed Group Corporation 5.2.9.14 Innocol, Inc. 5.2.9.15 Integra Life Sciences Holdings Corp. 5.2.9.16 Laboratoires Urgo 5.2.9.17 L.A.M. Pharmaceutical Corp. 5.2.9.18 Lifewave Ltd 5.2.9.19 Longport Inc. 5.2.9.20 Nagor Ltd. 5.2.9.21 SSL International Plc 5.2.9.22 Swiss American Products, Inc. 5.2.9.22.1 Wound Care Products
Appendix: LIST OF COMPANIES
List of Exhibits
Exhibit ES-1: Advanced Wound Care Market, by Segment, 2007 & 2016 Exihbit ES-2: Advanced Wound Care Market Shares by Competitor, 2007
Exhibit 1-1: Worldwide Wound Incidence by Etiology, 2007 Exhibit 1-2: Advanced Wound Management, Worldwide Market Forecast, 2007-2016 Exhibit 1-3: Total World Wound Management Products, Market Forecast, 2005-2014
Exhibit 2-1: Classification of Wounds by Etiology Exhibit 2-2: Old and New Classification Systems for Burns Exhibit 2-3: Distribution of Pressure Ulcers
Exhibit 3-1: Companies and Products in the Film Dressings Category Exhibit 3-2: Film Dressings, Worldwide Market Forecast, 2007-2016 Exhibit 3-3: Film Dressings, Worldwide Market Share by Supplier, 2007 Exhibit 3-4: Companies and Products in the Hydrocolloid Dressings Category Exhibit 3-5: Hydrocolloid Dressings, Worldwide Market Forecast, 2007-2016 Exhibit 3-6: Hydrocolloid Dressings, Worldwide Market Share by Supplier, 2007 Exhibit 3-7: Companies and Products in the Foam Dressings Category Exhibit 3-8: Foam Dressings, Worldwide Market Forecast, 2007-2016 Exhibit 3-9: Foam Dressings, Worldwide Market Share by Supplier, 2007 Exhibit 3-10: Companies and Products in the Alginate Dressings Category Exhibit 3-11: Alginate Dressings, Worldwide Market Forecast, 2007-2016 Exhibit 3-12: Alginate Dressings, Worldwide Market Share by Supplier, 2007 Exhibit 3-13: Amorphous Hydrogels - Companies and Products Exhibit 3-14: Impregnated Hydrogels – Companies and Products Exhibit 3-15: Sheet Hydrogels -Companies and Products Exhibit 3-16: Hydrogel Dressings, Worldwide Market Forecast, 2007- 2016 Exhibit 3-17: Hydrogel Dressings, Worldwide Market Share by Supplier, 2007 Exhibit 3-18: Companies and Products in the Non-Adherent Dressings Category Exhibit 3-19: Non-Adherent Wound Contact Layer Dressings, Worldwide Market
Forecast, 2007-2016 Exhibit 3-20: Non-Adherent Wound Contact Layer Dressings, Worldwide Market Share
by Supplier, 2007 Exhibit 3-21: Companies and Products in the Dressings Category Exhibit 3-22: Antimicrobial Dressings, Worldwide Market Forecast, 2007-2016 Exhibit 3-23: Antimicrobial Dressings, Worldwide Market Share by Supplier, 2007 Exhibit 3-24: Companies and Products in the Tissue Engineering Category Exhibit 3-25: Skin Tissue Engineering Market, Worldwide Market Forecast,
2007-2016 Exhibit 3-26: Tissue Engineering, Worldwide Share by Supplier, 2007 Exhibit 3-27: Growth Factors in Wound Care, Worldwide Market Forecast, 2007-2016 Exhibit 3-28: Companies Commercializing Technologies in the Physical Active
Treatments Category Exhibit 3-29: Physical Wound Therapies, Worldwide Market Forecast, 2007-2016
Exhibit 4-1: Summary Market Forecasts for Major Advanced Wound Management
Product Groups, 2007-2016 Exhibit 4-2: Leading Global Wound Care Companies Exhibit 4-3: Leading Global Wound Care Companies, Market Share 2007 Exhibit 4-4: National Shares of the Global Advanced Wound Management Market,
2007 Exhibit 4-5: Forecast U.S. Sales for Advanced Wound Management Products for the
Period 2007-2016 Exhibit 4-6: Forecast U.S. Sales Growth for the Main Types of Advanced Wound
Management Products for the Period 2007-2016 Exhibit 4-7: Japanese Sales for Advanced Wound Management Products for the
Period 2007-2016 Exhibit 4-8: Japanese Sales Growth for the Main Types of Advanced Wound
Management Products for the Period 2007-2016 Exhibit 4-9: German Sales for Advanced Wound Management Products for the Period
2007-2016 Exhibit 4-10: German Sales Growth for the Main Types of Advanced Wound
Management Products for the Period 2007-2016 Exhibit 4-11: French Sales for Advanced Wound Management Products for the period
2007-2016 Exhibit 4-12: French Sales Growth for the Main Types of Advanced Wound
Management Products for the Period 2007-2016: $ millions Exhibit 4-13: Italian Sales for Advanced Wound Management Products for the
Period 2007-2016: $ millions Exhibit 4-14: Italian Sales Growth for the Main Types of Advanced Wound
Management Products for the period 2007-2016: $millions Exhibit 4-15: UK Sales for Advanced Wound Management Products for the Period
2007-2016 Exhibit 4-16: UK Sales Growth for the Main Types of Advanced Wound Management
Products for the Period 2007-2016
Exhibit 5-1: Carrington Laboratories Financial Highlights Exhibit 5-2: Coloplast Revenue Growth by Business Area Exhibit 5-3: Derma Sciences, 1st Quarter 2007 Exhibit 5-4: Johnson & Johnson Member Companies Exhibit 5-5: Ethicon Sales, 2004-2006; $ millions Exhibit 5-6: Hartmann Historic Sales and Profit Data, Reported in €’000 Exhibit 5-7: 3M Healthcare Exhibit 5-8: Mölnlycke Health Care AB Revenues Exhibit 5-9: Smith & Nephew Financials, Q1-Q3, 2007 Exhibit 5-10: Recent Top-Line Financial Data for Mylan Exhibit 5-11: Advanced Wound Management Products and Suppliers
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